Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19635882 | 0.87 | OPRM1 (0.51) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL27090796 | 0.86 | CARM1 (0.45) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL15866116 | 0.82 | OPRD1 (0.35) | OPRM1OPRL1 | |
| SCHEMBL19181061 | 0.78 | CTSL (0.43) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL21598847 | 0.77 | OPRM1 (0.53) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL31172282 | 0.76 | THRB (0.35) | SIGMAR1 | |
| SCHEMBL31172293 | 0.75 | FUCA1 (0.45) | OPRL1SIGMAR1 | |
| SCHEMBL31190829 | 0.75 | HSD11B1 (0.39) | OPRL1SIGMAR1 | |
| SCHEMBL16080213 | 0.75 | ACHE (0.45) | SIGMAR1 | |
| SCHEMBL15866083 | 0.75 | FUCA1 (0.45) | OPRL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725442-B2 | Heterocyclic derivative having PGD2 receptor antagonist activity | SHIONOGI & CO., LTD. (JP) | 2017-08-08 | — | — | US | disclosed |