SCHEMBL11299734

SCHEMBL11299734

COC1(OC)C=CC(C(=O)c2cccc(O)c2)C(O)=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA6 P23280 1/20 0.38
CA9 Q16790 1/20 0.38
PARP1 P09874 1/20 0.37
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 3/20 0.36
EGLN2 Q96KS0 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
MGLL Q99685 6/20 0.35
ALDH1A1 P00352 1/20 0.35
NR1H4 Q96RI1 2/20 0.34
P4HB P07237 1/20 0.34
FASN P49327 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9461049 0.87 CES2 (0.47) PARP1NPC1RAB9AESR1ESR2
SCHEMBL3120601 0.86 TSHR (0.36) KDM4EALDH1A1GAAMAPT
SCHEMBL337246 0.76 LMNA (0.41) CA12CA1CA2CA6CA9
SCHEMBL8520514 0.74 PIN1 (0.40) CA12CA1CA2CA9NPC1
SCHEMBL23668760 0.72 NPC1 (0.34) NPC1RAB9AKDM4EALDH1A1GAA
SCHEMBL9732807 0.70 TSHR (0.34) PARP1POLBKDM4EALDH1A1GAA
SCHEMBL10615097 0.70 LMNA (0.38) ALDH1A1GAAMAPT
SCHEMBL158108 0.65 HTT (0.36) MGLLALDH1A1MAPT
SCHEMBL3037090 0.64 TSHR (0.36) ALDH1A1GAAMAPT
SCHEMBL210844 0.63 TSHR (0.41) ALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115244113-A Multilayer film 日本玛泰株式会社 2022-10-25 CN disclosed
US-4299886-A WITH POLYSILOXANES DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1981-11-10 US disclosed