Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016883 | 0.81 | HCAR1 (0.47) | ALDH1A1KDM4EMAPTHCAR1KMT2A | |
| SCHEMBL7278926 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTATMKMT2A | |
| SCHEMBL31040870 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2ALMNANOS1 | |
| SCHEMBL11411912 | 0.79 | HCAR1 (0.45) | ALDH1A1KDM4EMAPTHCAR1KMT2A | |
| SCHEMBL8081306 | 0.77 | MAPT (0.50) | ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL31137279 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL31500097 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL7981240 | 0.76 | KMT2A (0.48) | ALDH1A1KDM4EMAPTHCAR1KMT2A | |
| SCHEMBL8027450 | 0.75 | HCAR1 (0.50) | ALDH1A1KDM4EMAPTHCAR1KMT2A | |
| SCHEMBL14428964 | 0.74 | CYP3A4 (0.50) | ALDH1A1KDM4EMAPTHCAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327411-A1 | SIRT6 ACTIVATORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2024-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327411-A1 | SIRT6 ACTIVATORS | SIRT6, SIRT1, SIRT2 | ALDH1A1 1699/4885KDM4E 1274/4885MAPT 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.