Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016883 | 0.75 | HCAR1 (0.47) | HCAR1ALDH1A1MAPTL3MBTL1MET | |
| SCHEMBL31213128 | 0.75 | ALDH1A1 (0.61) | HCAR1ALDH1A1MAPTL3MBTL1MET | |
| SCHEMBL3078101 | 0.73 | KAT2B (0.48) | ALDH1A1MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL11411912 | 0.73 | HCAR1 (0.45) | HCAR1ALDH1A1MAPTL3MBTL1MET | |
| SCHEMBL30426426 | 0.72 | ALDH1A1 (0.52) | HCAR1ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL5242261 | 0.72 | ALDH1A1 (0.52) | HCAR1ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL6219384 | 0.71 | NPC1 (0.54) | ALDH1A1L3MBTL1LMNARAB9ANPC1 | |
| SCHEMBL1321811 | 0.70 | KMT2A (0.74) | HCAR1ALDH1A1MAPTHTTPOLB | |
| SCHEMBL27814208 | 0.70 | ALDH1A1 (0.47) | HCAR1ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL7981240 | 0.70 | KMT2A (0.48) | HCAR1ALDH1A1MAPTLMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738713-B1 | Process for the preparation of pesticidal 1-(chloroaryl)heterocyclic compounds | RHONE POULENC AGROCHIMIE (FR) | 2000-02-09 | — | — | EP | disclosed |
| US-5726324-A | 1-(nitroaryl)pyrrole intermediates to pesticidal 1-(haloaryl)pyrroles | RHONE-POULENC INC. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5631381-A | Process for the preparation of pesticidal 1-(haloaryl) heterocyclic compounds | RHONE-POULENC INC. (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0738713-A1 | Process for the preparation of pesticidal 1-(haloaryl)heterocyclic compounds | RHONE-POULENC AGROCHIMIE (FR) | 1996-10-23 | — | — | EP | disclosed |