Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31213128 | 0.81 | ALDH1A1 (0.61) | HCAR1ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL11411912 | 0.79 | HCAR1 (0.45) | HCAR1ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL7981240 | 0.76 | KMT2A (0.48) | HCAR1ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL8027450 | 0.75 | HCAR1 (0.50) | HCAR1ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL8081306 | 0.72 | MAPT (0.50) | ALDH1A1KDM4EMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL8699160 | 0.71 | ALDH1A1 (0.42) | HCAR1ALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL9402020 | 0.71 | KMT2A (0.45) | ALDH1A1MAPTHTTKMT2AGAA | |
| SCHEMBL7279344 | 0.70 | THRB (0.48) | ALDH1A1KDM4EMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL8653890 | 0.70 | FGFR1 (0.53) | ALDH1A1KDM4EMAPTFGFR1KMT2A | |
| SCHEMBL4453426 | 0.69 | KMT2A (0.44) | HCAR1ALDH1A1MAPTL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046277-C | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1999-11-10 | — | — | CN | disclosed |
| US-5541198-A | ANTISTICKING AGENTS FOR PLATELETS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-30 | — | — | US | disclosed |
| EP-0651747-B1 | CARBOSTYRYL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| EP-0651747-A1 | CARBOSTYRIL DERIVATIVES. | OTSUKA PHARMA CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994026732-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |