SCHEMBL312260

SCHEMBL312260

O=C(OCCCl)c1cccnc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.68
LMNA P02545 4/20 0.64
KMT2A Q03164 4/20 0.60
TDP1 Q9NUW8 2/20 0.60
ALDH1A1 P00352 5/20 0.60
KDM4E B2RXH2 2/20 0.60
MEN1 O00255 2/20 0.58
USP2 O75604 2/20 0.58
GAA P10253 2/20 0.57
MAPT P10636 3/20 0.55
MAPK1 P28482 1/20 0.55
HPGD P15428 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
AGTR1 P30556 1/20 0.55
CYP2C19 P33261 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.54
PKM P14618 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31023467 1.00 L3MBTL1 (0.68) L3MBTL1LMNAKMT2ATDP1ALDH1A1
SCHEMBL25009812 0.90 L3MBTL1 (0.76) L3MBTL1LMNAKMT2ATDP1ALDH1A1
SCHEMBL30556174 0.90 L3MBTL1 (0.76) L3MBTL1LMNAKMT2ATDP1ALDH1A1
SCHEMBL29155474 0.89 LMNA (0.72) L3MBTL1LMNAKMT2ATDP1ALDH1A1
SCHEMBL10884343 0.88 LMNA (0.74) L3MBTL1LMNAKMT2ATDP1ALDH1A1
SCHEMBL837646 0.86 LMNA (0.64) L3MBTL1LMNAKMT2ATDP1ALDH1A1
SCHEMBL21243071 0.86 LMNA (0.82) L3MBTL1LMNAKMT2ATDP1ALDH1A1
SCHEMBL25009811 0.86 L3MBTL1 (0.82) L3MBTL1LMNAKMT2ATDP1ALDH1A1
SCHEMBL5363082 0.85 LMNA (0.71) L3MBTL1LMNAKMT2ATDP1ALDH1A1
SCHEMBL9717090 0.85 L3MBTL1 (0.69) L3MBTL1LMNAKMT2ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107540605-A For hair or the choline ester type compound of scalp care 李明霞 2018-01-05 CN claimed
US-20260027096-A1 PHD INHIBITORS UNIV OXFORD INNOVATION LTD (GB) 2026-01-29 US disclosed
EP-4655288-A1 PHD INHIBITORS Oxford University Innovation Limited (GB) 2025-12-03 EP disclosed
EP-4655294-A1 PYRAZOLE DERIVSTIVES AS PHD INHIBITORS Oxford University Innovation Limited (GB) 2025-12-03 EP disclosed
WO-2024157014-A1 PYRAZOLE DERIVSTIVES AS PHD INHIBITORS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2024-08-02 WO disclosed
WO-2024157019-A1 PHD INHIBITORS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2024-08-02 WO disclosed
EP-3426246-B1 THIAZOLIDINONE COMPOUNDS AND USE THEREOF NATIONAL HEALTH RES INST (TW) 2024-05-01 EP disclosed
CN-115872928-A Method for preparing pyridine chloride 3-choline formate 宁波见睿新材料有限公司 2023-03-31 CN disclosed
CN-108883099-B Thiazolidinone compounds and use thereof 石全 2021-09-28 CN disclosed
CN-107540605-B Choline esters for hair or scalp care 宁波见睿新材料有限公司 2020-03-06 CN disclosed
EP-2314295-A1 Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices Resverlogix, Inc (CA) 2011-04-27 EP disclosed
US-20090259048-A1 FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES RESVERLOGIX CORP. (CA) 2009-10-15 US disclosed
CN-101365446-A Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery via implantable medical devices RESVERLOGIX CORP (CA) 2009-02-11 CN disclosed
US-20090029987-A1 Pharmaceutical Compositions for the Prevention and Treatment of Complex Diseases and Their Delivery by Insertable Medical Devices RESVERLOGIX CORP. (CA) 2009-01-29 US disclosed
EP-1909788-A2 PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES RESVERLOGIX CORP. (CA) 2008-04-16 EP disclosed
EP-1838296-A2 FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES RESVERLOGIX CORP. (CA) 2007-10-03 EP disclosed
WO-2007016525-A2 PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES RESVERLOGIX CORP. (CA) 2007-02-08 WO disclosed
US-20060205767-A1 Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases HEPALINK (HONG KONG) LIMITED (HK) 2006-09-14 US disclosed
WO-2006045096-A2 FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES RESVERLOGIX CORP. (CA) 2006-04-27 WO disclosed
EP-0489581-A2 Cosmetic composition UNILEVER PLC (GB) 1992-06-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060205767-A1 Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases APOB, APOL1, FABP3 L3MBTL1 3437/4885LMNA 345/4885KMT2A 2842/4885
US-20260027096-A1 PHD INHIBITORS HIF1AN, HIF1A, EGLN1 L3MBTL1 215/4885LMNA 1934/4885KMT2A 37/4885
US-20090259048-A1 FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES APOB, APOL1, FABP3 L3MBTL1 3437/4885LMNA 345/4885KMT2A 2842/4885
US-20090029987-A1 Pharmaceutical Compositions for the Prevention and Treatment of Complex Diseases and Their Delivery by Insertable Medical Devices VCAM1, ICAM1, TGFB1 L3MBTL1 4211/4885LMNA 1518/4885KMT2A 3207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.