SCHEMBL3122834

SCHEMBL3122834

Fc1ccc2c(C3CCN(CCCCl)CC3)noc2c1

nearest known ligand 0.77

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.77
DRD2 P14416 7/20 0.75
SLC6A4 P31645 1/20 0.75
HTR1A P08908 6/20 0.69
HTR2A P28223 6/20 0.69
HRH3 Q9Y5N1 6/20 0.69
HTR2C P28335 2/20 0.67
ADRA1A P35348 2/20 0.67
HRH1 P35367 2/20 0.67
DRD3 P35462 2/20 0.67
HTR6 P50406 2/20 0.67
KCNH2 Q12809 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1836420 0.97 ACHE (0.75) ACHEDRD2SLC6A4HTR1AHTR2A
SCHEMBL6182384 0.93 ACHE (0.80) ACHEDRD2SLC6A4HTR1AHTR2A
SCHEMBL1545611 0.90 ACHE (0.93) ACHEDRD2SLC6A4HTR1AHTR2A
SCHEMBL1544799 0.88 ACHE (0.77) ACHEDRD2SLC6A4HTR2AKCNH2
SCHEMBL7351897 0.88 ACHE (0.91) ACHEDRD2SLC6A4HTR1AHTR2A
SCHEMBL791116 0.88 ACHE (0.77) ACHEDRD2SLC6A4HTR1AHTR2A
SCHEMBL7355656 0.88 ACHE (0.77) ACHEDRD2SLC6A4HTR1AHTR2A
SCHEMBL1545556 0.87 ACHE (0.75) ACHEDRD2SLC6A4HTR1AHTR2A
Hydrochloric Acid SCHEMBL1544617 0.87 ACHE (0.75) ACHEDRD2SLC6A4HTR1AHTR2A
SCHEMBL791471 0.87 ACHE (0.75) ACHEDRD2SLC6A4HTR1AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102455329-B Method for analyzing iloperidone and relevant substances thereof through high performance liquid chromatography (HPLC) CHONGQING PHARM RES INST CO 2015-02-25 CN claimed
US-20100076196-A1 PROCESS FOR THE PREPARATION OF ILOPERIDONE VERTESSY MIKLOS 2010-03-25 US claimed
WO-2010031497-A1 NEW PROCESS FOR THE PREPARATION OF ILOPERIDONE MIKLOS VERTESSY (HU) 2010-03-25 WO claimed
EP-4463455-B1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS SUVEN LIFE SCIENCES LTD (IN) 2026-04-29 EP disclosed
US-12391698-B2 Substituted piperidines and piperazines and methods for the treatment of CNS disorders SUVEN LIFE SCIENCES LIMITED (IN) 2025-08-19 US disclosed
US-12338236-B2 Benzoisothiazole and benzoisoxazole compounds for the treatment of mental disorders SUVEN LIFE SCIENCES LIMITED (IN) 2025-06-24 US disclosed
US-20250101014-A1 BENZOISOTHIAZOLE AND BENZOISOXAZOLE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS SUVEN LIFE SCIENCES LIMITED (IN) 2025-03-27 US disclosed
US-20250092049-A1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS SUVEN LIFE SCIENCES LIMITED (IN) 2025-03-20 US disclosed
EP-4469453-A1 BENZOISOTHIAZOLE AND BENZOISOXAZOLE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS Suven Life Sciences Limited (IN) 2024-12-04 EP disclosed
EP-4463455-A1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS Suven Life Sciences Limited (IN) 2024-11-20 EP disclosed
CN-118647615-A Benzisothiazole and benzisoxazole compounds for the treatment of psychotic disorders 苏文生命科学有限公司 2024-09-13 CN disclosed
WO-2012063269-A2 PROCESS FOR PREPARING ILOPERIDONE CADILA HEALTHCARE LIMITED (IN) 2012-05-18 WO disclosed
US-20100076196-A1 PROCESS FOR THE PREPARATION OF ILOPERIDONE VERTESSY MIKLOS 2010-03-25 US disclosed
US-20100076196-A1 PROCESS FOR THE PREPARATION OF ILOPERIDONE VERTESSY MIKLOS 2010-03-25 US disclosed
US-20100076196-A1 PROCESS FOR THE PREPARATION OF ILOPERIDONE VERTESSY MIKLOS 2010-03-25 US disclosed
US-20100076196-A1 PROCESS FOR THE PREPARATION OF ILOPERIDONE VERTESSY MIKLOS 2010-03-25 US disclosed
WO-2010031497-A1 NEW PROCESS FOR THE PREPARATION OF ILOPERIDONE MIKLOS VERTESSY (HU) 2010-03-25 WO disclosed
EP-1275641-B1 Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2005-01-12 EP disclosed
US-6541471-B1 Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist LES LABORATOIRES SERVIER (FR) 2003-04-01 US disclosed
EP-1275641-A2 Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them Les Laboratoires Servier (FR) 2003-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250101014-A1 BENZOISOTHIAZOLE AND BENZOISOXAZOLE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS GABRA5, GABBR1, GABRA2 ACHE 855/4885DRD2 426/4885SLC6A4 61/4885
US-12391698-B2 Substituted piperidines and piperazines and methods for the treatment of CNS disorders GRIN2C, SLC1A2, CNR2 ACHE 322/4885DRD2 62/4885SLC6A4 60/4885
US-20100076196-A1 PROCESS FOR THE PREPARATION OF ILOPERIDONE IL2, IL17A, IL4 ACHE 4241/4885DRD2 3537/4885SLC6A4 4609/4885
US-20250092049-A1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS GRIN2C, CNR2, INA ACHE 175/4885DRD2 249/4885SLC6A4 63/4885
US-12338236-B2 Benzoisothiazole and benzoisoxazole compounds for the treatment of mental disorders GABRA5, GABBR1, GABRA2 ACHE 855/4885DRD2 426/4885SLC6A4 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.