Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.80 |
| ▸ | DRD2 | P14416 | 7/20 | 0.78 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.78 |
| ▸ | HTR2A | P28223 | 6/20 | 0.63 |
| ▸ | HTR1A | P08908 | 4/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122834 | 0.93 | ACHE (0.77) | ACHEDRD2SLC6A4HTR2AHTR1A | |
| SCHEMBL1545611 | 0.92 | ACHE (0.93) | ACHEDRD2SLC6A4HTR2AHTR1A | |
| SCHEMBL1836420 | 0.92 | ACHE (0.75) | ACHEDRD2SLC6A4HTR2AHTR1A | |
| SCHEMBL22048381 | 0.90 | ACHE (0.65) | ACHEDRD2SLC6A4HTR2AHTR1A | |
| SCHEMBL7351612 | 0.88 | ACHE (0.80) | ACHEDRD2SLC6A4HTR2AHTR1A | |
| SCHEMBL1544908 | 0.88 | ACHE (0.84) | ACHEDRD2SLC6A4HTR2AHTR1A | |
| SCHEMBL1545195 | 0.88 | ACHE (0.80) | ACHEDRD2SLC6A4HTR2AKCNH2 | |
| SCHEMBL7722977 | 0.88 | ACHE (0.80) | ACHEDRD2SLC6A4HTR2AKCNH2 | |
| SCHEMBL793025 | 0.88 | ACHE (0.80) | ACHEDRD2SLC6A4HTR2AKCNH2 | |
| SCHEMBL791116 | 0.86 | ACHE (0.77) | ACHEDRD2SLC6A4HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981264-B | Fatty acid amide derivatives | 住友制药株式会社 | 2024-07-26 | — | — | CN | disclosed |
| US-20230008875-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | Sumitomo Pharma Co., Ltd. (JP) | 2023-01-12 | — | — | US | disclosed |
| CN-114981264-A | Fatty acid amide derivatives | 住友制药株式会社 | 2022-08-30 | — | — | CN | disclosed |
| US-20220213079-A1 | ALIPHATIC ACID AMIDE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-07-07 | — | — | US | disclosed |
| US-11339151-B2 | Aliphatic acid amide derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-05-24 | — | — | US | disclosed |
| US-20220073506-A1 | ALIPHATIC ACID AMIDE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-03-10 | — | — | US | disclosed |
| WO-2021132311-A1 | ALIPHATIC ACID AMIDE DERIVATIVE | 大日本住友製薬株式会社 | 2021-07-01 | — | — | WO | disclosed |
| WO-2021132311-A1 | ALIPHATIC ACID AMIDE DERIVATIVE | 大日本住友製薬株式会社 | 2021-07-01 | — | — | WO | disclosed |
| EP-3828182-A1 | FUSED RING LACTAM DERIVATIVES | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-10745401-B2 | Condensed lactam derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-08-18 | — | — | US | disclosed |
| US-20200255432-A1 | CONDENSED LACTAM DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-08-13 | — | — | US | disclosed |
| US-20200172543-A1 | CONDENSED LACTAM DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | disclosed |
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |
| EP-1275641-A2 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255432-A1 | CONDENSED LACTAM DERIVATIVE | PSEN1, GRIN1, HDAC1 | ACHE 94/4885DRD2 430/4885SLC6A4 407/4885 |
| US-11339151-B2 | Aliphatic acid amide derivative | HTR2A, HTR1A, HTR7 | ACHE 1920/4885DRD2 15/4885SLC6A4 36/4885 |
| US-10745401-B2 | Condensed lactam derivative | PSEN1, GRIN1, HDAC1 | ACHE 94/4885DRD2 430/4885SLC6A4 407/4885 |
| US-20230008875-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | HTR1A, HTR5A, TPH1 | ACHE 200/4885DRD2 59/4885SLC6A4 19/4885 |
| US-20200172543-A1 | CONDENSED LACTAM DERIVATIVE | PSEN1, GRIN1, HDAC1 | ACHE 94/4885DRD2 430/4885SLC6A4 407/4885 |
| US-20220213079-A1 | ALIPHATIC ACID AMIDE DERIVATIVE | HTR2A, HTR1A, HTR7 | ACHE 1920/4885DRD2 15/4885SLC6A4 36/4885 |
| US-20220073506-A1 | ALIPHATIC ACID AMIDE DERIVATIVE | HTR2A, HTR1A, HTR7 | ACHE 1920/4885DRD2 15/4885SLC6A4 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.