Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 5/20 | 0.38 |
| ▸ | CDK9 | P50750 | 5/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240455 | 0.94 | TGFBR1 (0.39) | CCNT1CDK9TGFBR1TRPA1PIK3CA | |
| SCHEMBL31240449 | 0.92 | CCNT1 (0.39) | CCNT1CDK9TGFBR1TRPA1PIK3CA | |
| SCHEMBL31240766 | 0.83 | AURKA (0.47) | CCNT1CDK9TGFBR1TRPA1PIK3CA | |
| SCHEMBL31240731 | 0.81 | ROCK2 (0.44) | CCNT1CDK9TRPA1PIK3CAROCK2 | |
| SCHEMBL31240583 | 0.77 | CLK2 (0.42) | CCNT1CDK9WNT1ROCK2MAP4K4 | |
| SCHEMBL31240632 | 0.76 | CLK2 (0.41) | CCNT1CDK9WNT1ROCK2MAP4K4 | |
| SCHEMBL31240648 | 0.71 | TRPA1 (0.41) | TGFBR1TRPA1PIK3CACCNKCDK12 | |
| SCHEMBL31240575 | 0.70 | MAP3K11 (0.41) | CDK9PIK3CACCNKCDK12PRKCQ | |
| SCHEMBL31240759 | 0.70 | CDK9 (0.40) | CCNT1CDK9CDC7PIM1GSK3B | |
| SCHEMBL31240369 | 0.67 | CHUK (0.47) | CCNT1CDK9WNT1CLK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |