Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL820095 | 0.88 | PNMT (0.33) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL3006006 | 0.81 | NPC1 (0.37) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL4481194 | 0.81 | PNMT (0.33) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL3124487 | 0.81 | NPC1 (0.49) | NPC1RAB9APNMTALDH1A1HTR7 | |
| Hydrochloric Acid SCHEMBL676093 | 0.80 | NPC1 (0.32) | NPC1RAB9ADRD2 | |
| Hydrochloric Acid SCHEMBL674374 | 0.80 | NPC1 (0.32) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6553935 | 0.80 | NPC1 (0.38) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL3015454 | 0.78 | NPC1 (0.34) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL3005060 | 0.78 | NPC1 (0.34) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL3011448 | 0.78 | NPC1 (0.34) | NPC1RAB9APNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8373011-B2 | Used in a base oil of lubricant having good low temperature fluidity, low evaporativity, and thermal stability and oxidation stability | IDEMITSU KOSAN CO., LTD. (JP) | 2013-02-12 | — | — | US | disclosed |
| US-20120088946-A1 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2012-04-12 | — | — | US | disclosed |
| US-8119850-B2 | Process for producing unsaturated hydrocarbon compound | IDEMITSU KOSAN CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| EP-0945471-B1 | CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS | IDEMITSU KOSAN CO (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-20090069614-A1 | METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20090030255-A1 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20080146469-A1 | Process for producing saturated aliphatic hydrocarbon compound, and lubricant composition | IDEMITSU KOSAN CO., LTD. (JP) | 2008-06-19 | — | — | US | disclosed |
| EP-1880986-A1 | PROCESS FOR PRODUCING SATURATED ALIPHATIC HYDROCARBON COMPOUND, AND LUBRICANT COMPOSITION | IDEMITSU KOSAN CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |
| EP-1849757-A1 | METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-6787499-B2 | Catalyst for the production of α-olefin and α-olefin production method | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-0589638-A2 | Powder catalyst composition and process for polymerizing olefins with the use thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-03-30 | — | — | EP | disclosed |
| EP-0574258-A2 | Process for producing alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1993-12-15 | — | — | EP | disclosed |
| EP-0570126-A1 | Method for producing graft-modified copolymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1993-11-18 | — | — | EP | disclosed |
| EP-0566349-A2 | Process for producing alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5252677-A | Epoxy, hydroxy or sulfonic acid end groups | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1993-10-12 | — | — | US | disclosed |
| US-5225501-A | Transition metal compound and alumoxane catalyst | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0512741-A1 | Process for producing a propylene random copolymer | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-11-11 | — | — | EP | disclosed |
| EP-0511846-A1 | Aminated olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-11-04 | — | — | EP | disclosed |
| EP-0498675-A2 | Production of alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-08-12 | — | — | EP | disclosed |
| EP-0487278-A2 | Functionalized olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030255-A1 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | ALOX12, ALOX15B, ALOX15 | NPC1 1027/4885RAB9A 4335/4885PNMT 1509/4885 |
| US-20090069614-A1 | METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | AHR, ALOX12, ARNT | NPC1 684/4885RAB9A 4259/4885PNMT 2343/4885 |
| US-20080146469-A1 | Process for producing saturated aliphatic hydrocarbon compound, and lubricant composition | ALOX15, ALOX12, ALOX15B | NPC1 2750/4885RAB9A 4124/4885PNMT 3641/4885 |
| US-20120088946-A1 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | ALOX12, ALOX15B, ALOX15 | NPC1 1027/4885RAB9A 4335/4885PNMT 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.