SCHEMBL3128301

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12569390	0.90	HTR6 (0.56)	HTR6FFAR1HTR2CMETAP2HTT
	SCHEMBL3128097	0.85	HTR6 (0.57)	HTR6MAOAHTR2A
	SCHEMBL3130643	0.85	L3MBTL1 (0.58)	HTR6MAOAHTR2A
	SCHEMBL15576268	0.83	HDAC4 (0.56)	FFAR1METAP2HTT
	SCHEMBL1681160	0.82	HTR6 (0.54)	HTR6FFAR1HTR2CMETAP2HTT
	SCHEMBL6690772	0.80	HTT (0.57)	FFAR1HTR2CMETAP2HTTPTPN1
	SCHEMBL3131791	0.79	CHRM2 (0.50)	HTR6
	SCHEMBL28855181	0.77	FFAR1 (0.53)	FFAR1HTR2CMETAP2HTTPTPN1
	SCHEMBL3128386	0.76	GHSR (0.52)	HTR6HTTHTR2A
	SCHEMBL613208	0.76	MAOA (0.68)	HTR6HTR2CMAOAHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.