Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27539610 | 0.78 | — | — | |
| SCHEMBL87430 | 0.77 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL146478 | 0.77 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL3309545 | 0.77 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL3306685 | 0.74 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| SCHEMBL49735 | 0.74 | — | — | |
| SCHEMBL11027407 | 0.73 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| Bromide SCHEMBL11805140 | 0.72 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| Hydrochloric Acid SCHEMBL31200743 | 0.72 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| Hydrochloric Acid SCHEMBL20424103 | 0.72 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3HRH1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179423-A | TERTIARY AMINE, TRIOL, TRICARBOXYLIC ACID ANHYDRIDE | SCHENECTADY CHEMICALS, INC. (US) | 1979-12-18 | — | — | US | claimed |
| US-9914709-B2 | Compositions and methods of treating HIV-1 infections using same | YALE UNIVERSITY (US) | 2018-03-13 | — | — | US | disclosed |
| US-9631045-B2 | Polycarbodiimides having onium salt groups | PPG INDUSTRIES OHIO, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-8981005-B2 | Coating compositions that include onium salt group containing polycarbodiimides | PPG INDUSTRIES OHIO, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8952006-B2 | Morpholinoalkyl fumarate compounds, pharmaceutical compositions, and methods of use | XENOPORT, INC. (US) | 2015-02-10 | — | — | US | disclosed |
| US-20140378443-A1 | Novel Compositions and Methods of Treating HIV-1 Infections Using Same | YALE UNIVERSITY | 2014-12-25 | — | — | US | disclosed |
| EP-2812319-A1 | MORPHOLINOALKYL FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE | XenoPort, Inc. (US) | 2014-12-17 | — | — | EP | disclosed |
| US-20140051705-A1 | Morpholinoalkyl Fumarate Compounds, Pharmaceutical Compositions, and Methods of Use | XENOPORT, INC. (US) | 2014-02-20 | — | — | US | disclosed |
| WO-2013119791-A1 | MORPHOLINOALKYL FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE | XENOPORT, INC. (US) | 2013-08-15 | — | — | WO | disclosed |
| US-20130203753-A1 | MORPHOLINOALKYL FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE | XENOPORT, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| EP-0303555-B1 | Preparation of a metallic chelate of ethanol aminophosphoric acid and medicament | KOEHLER CHEMIE DR FRANZ (DE) | 1994-06-15 | — | — | EP | disclosed |
| EP-0426826-B1 | SUBSTITUTED ISOXAZOLIDINES AND ISOXAZOLINES | PHARMACIA AB (SE) | 1994-04-27 | — | — | EP | disclosed |
| US-5212305-A | Cyclization and forming a carbon-nitrogen bond | KABI PHARMACIA AKTIBOLAG (SE) | 1993-05-18 | — | — | US | disclosed |
| US-5155220-A | Simplified production of plaque inhibitor | KABI PHARMACIA AKTIEBOLAG (SE) | 1992-10-13 | — | — | US | disclosed |
| EP-0426826-A1 | SUBSTITUTED ISOXAZOLIDINES AND ISOXAZOLINES. | PHARMACIA AB (SE) | 1991-05-15 | — | — | EP | disclosed |
| WO-1990014342-A1 | SUBSTITUTED ISOXAZOLIDINES AND ISOXAZOLINES | PHARMACIA AB (SE) | 1990-11-29 | — | — | WO | disclosed |
| EP-0303555-A2 | Preparation of a metallic chelate of ethanol aminophosphoric acid and medicament | Dr. Franz Köhler Chemie GmbH (DE) | 1989-02-15 | — | — | EP | disclosed |
| US-4582904-A | REACTING ORGANIC HYDROXY COMPOUND WITH AMMONIA OR AMINE COMPOUND | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-04-15 | — | — | US | disclosed |
| US-4560798-A | SELF CONDENSATION OF ETHANOLAMINE;HIGH SELECTIVITY | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-12-24 | — | — | US | disclosed |
| US-4048338-A | Aqueous cosmetic composition containing amine oxides | COLGATE-PALMOLIVE COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051705-A1 | Morpholinoalkyl Fumarate Compounds, Pharmaceutical Compositions, and Methods of Use | FH, APC, HTT | SLC6A2 4712/4885SLC6A4 3547/4885SLC6A3 3690/4885 |
| US-20130203753-A1 | MORPHOLINOALKYL FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE | FH, APC, HTT | SLC6A2 4712/4885SLC6A4 3547/4885SLC6A3 3690/4885 |
| US-20140378443-A1 | Novel Compositions and Methods of Treating HIV-1 Infections Using Same | CCR5, CCL5, CX3CR1 | SLC6A2 4284/4885SLC6A4 4641/4885SLC6A3 4218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.