Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27814274 | 0.82 | HSD11B1 (0.48) | HSD11B1TSHRRECQLHSD17B10POLB | |
| SCHEMBL11211866 | 0.80 | HSD11B1 (0.55) | HSD11B1TSHRRECQLHSD17B10POLB | |
| SCHEMBL4039494 | 0.80 | ALDH1A1 (0.58) | HSD11B1TSHRRECQLCYP3A4MAPT | |
| SCHEMBL2220361 | 0.80 | ALDH1A1 (0.55) | HSD11B1TSHRRECQLPOLBMAPT | |
| SCHEMBL30062 | 0.80 | ALDH1A1 (0.58) | HSD11B1TSHRRECQLCYP3A4MAPT | |
| SCHEMBL64274 | 0.80 | TDP1 (0.52) | HSD11B1TSHRRECQLHSD17B10POLB | |
| SCHEMBL3720381 | 0.80 | TDP1 (0.52) | HSD11B1TSHRRECQLHSD17B10POLB | |
| SCHEMBL28730355 | 0.79 | HSD11B1 (0.50) | HSD11B1TSHRRECQLHSD17B10POLB | |
| SCHEMBL2362058 | 0.78 | TDP1 (0.50) | HSD11B1TSHRRECQLHSD17B10POLB | |
| Bromide SCHEMBL7641961 | 0.78 | ALDH1A1 (0.56) | HSD11B1TSHRRECQLCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115012224-B | Waterproof plush and surface treatment process thereof | 苍南县永顺毛绒有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-115012224-A | Waterproof plush and surface treatment process thereof | 苍南县永顺毛绒有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-106366116-A | 2-Oxo-3-phenylpropionic acid p-methylbenzoyl hydrazone di-p-methylbenzyltin complex, and preparation method and application thereof | 衡阳师范学院 | 2017-02-01 | — | — | CN | claimed |
| US-8492440-B2 | Difluorophenyldiacylhydrazide derivatives | MERCK PATENT GMBH (DE) | 2013-07-23 | — | — | US | claimed |
| US-20110224302-A1 | DIFLUOROPHENYLDIACYLHYDRAZIDE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-09-15 | — | — | US | claimed |
| EP-2077841-A1 | NOVEL SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | Glaxo Group Limited (GB) | 2009-07-15 | — | — | EP | claimed |
| WO-2008052934-A1 | NOVEL SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2008-05-08 | — | — | WO | claimed |
| US-4617401-A | ANTISPASMODIC AGENTS, VASODILATORS | SUNTORY LTD. (JP) | 1986-10-14 | — | — | US | claimed |
| EP-0039903-B1 | 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF | SUNTORY KABUSHIKI KAISHA (JP) | 1986-04-09 | — | — | EP | claimed |
| US-20260042731-A1 | (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS | CORTEVA AGRISCIENCE LLC (US) | 2026-02-12 | — | — | US | disclosed |
| EP-4638436-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-10-29 | — | — | EP | disclosed |
| CN-119731146-A | (2, 4-Dichlorophenoxy) acetic acid analogues | 科迪华农业科技有限责任公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119677723-A | Difluoro and trifluoroacetyl hydrazides as selective HDAC6 inhibitors | 意大发马克股份公司 | 2025-03-21 | — | — | CN | disclosed |
| US-20240254118-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. | 2024-08-01 | — | — | US | disclosed |
| US-4418076-A | 7-Oxabicycloheptane hydrazone prostaglandin analogs useful in treating thrombolytic diseases | E. R. SQUIBB & SONS, INC. (US) | 1983-11-29 | — | — | US | disclosed |
| EP-0039903-A2 | 8-Substituted pyrrolizidines and quaternary ammonium salts thereof | SUNTORY KABUSHIKI KAISHA (JP) | 1981-11-18 | — | — | EP | disclosed |
| US-4205173-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |
| US-4151169-A | DECYCLIZATION, CYCLIZATION | GRUPPO LEPETIT (IT) | 1979-04-24 | — | — | US | disclosed |
| US-4119635-A | SEDATIVES, HYPNOTICS, TRANQUILIZERS | GRUPPO LEPETIT S.P.A. (IT) | 1978-10-10 | — | — | US | disclosed |
| US-4060526-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254118-A1 | PRMT5 INHIBITORS AND USES THEREOF | PRMT5, PRMT1, PRMT9 | HSD11B1 3030/4885TSHR 3833/4885RECQL 779/4885 |
| US-20260042731-A1 | (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS | DDT, AADAC, HACL2 | HSD11B1 356/4885TSHR 617/4885RECQL 2221/4885 |
| US-20110224302-A1 | DIFLUOROPHENYLDIACYLHYDRAZIDE DERIVATIVES | FGFR1, PKD1, AGTR1 | HSD11B1 1846/4885TSHR 115/4885RECQL 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.