SCHEMBL3128562

SCHEMBL3128562

CCCCCCCCN/C(C)=C\C(C)=O

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 10/20 0.57
ZDHHC20 Q5W0Z9 1/20 0.53
ZDHHC2 Q9UIJ5 1/20 0.53
CASP2 P42575 1/20 0.52
FAAH O00519 1/20 0.49
NAAA Q02083 1/20 0.48
EPHX2 P34913 4/20 0.47
KDM4E B2RXH2 1/20 0.46
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3128565 1.00 EPHX1 (0.57) EPHX1ZDHHC20ZDHHC2CASP2FAAH
SCHEMBL14148319 1.00 EPHX1 (0.57) EPHX1ZDHHC20ZDHHC2CASP2FAAH
SCHEMBL19066279 0.98 EPHX1 (0.54) EPHX1ZDHHC20ZDHHC2CASP2FAAH
SCHEMBL19066280 0.98 EPHX1 (0.54) EPHX1ZDHHC20ZDHHC2CASP2FAAH
SCHEMBL11753268 0.92 EPHX1 (0.48) EPHX1ZDHHC20ZDHHC2CASP2
SCHEMBL11753262 0.92 EPHX1 (0.48) EPHX1ZDHHC20ZDHHC2CASP2
SCHEMBL9017550 0.87 FAAH (0.46) EPHX1ZDHHC20ZDHHC2CASP2FAAH
SCHEMBL9433763 0.86 EPHX1 (0.55) EPHX1ZDHHC20ZDHHC2CASP2FAAH
SCHEMBL11571804 0.86 ZDHHC20 (0.61) EPHX1ZDHHC20ZDHHC2CASP2FAAH
SCHEMBL5701154 0.86 EPHX1 (0.55) EPHX1ZDHHC20ZDHHC2CASP2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1353642-B1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING AN AMPHIPHILIC COPOYLMER COMPRISING 2-ACRYLAMIDO-2-PROPANESULFONIC AND (METH)ACRYLATES OREAL (FR) 2008-05-07 EP claimed
US-7166274-B2 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds L'OREAL (FR) 2007-01-23 US claimed
US-7045120-B2 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers L'OREAL (FR) 2006-05-16 US claimed
EP-1093798-B1 Emulsions without emulsifiers containing at least one insoluble organic UV-filter OREAL (FR) 2005-08-31 EP claimed
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL S.A. (FR) 2004-04-15 US claimed
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SOCIETE L'OREAL S.A. (FR) 2004-03-11 US claimed
EP-1370232-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2003-12-17 EP claimed
EP-1353642-A1 AMPHIPHILIC POLYMER-BASED PHOTOPROTECTIVE COMPOSITIONS WITH AT LEAST ONE MONOMER HAVING ETHYLENIC UNSATURATION WITH A SULPHONIC GROUP AND COMPRISING A HYDROPHOBIC PART L'OREAL (FR) 2003-10-22 EP claimed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US claimed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 US claimed
US-6419908-B1 RADIATION RESISTANCE SOCIETE L'OREAL (FR) 2002-07-16 US claimed
US-6416748-B1 COMPRISING AQUEOUS AND FATTY PHASES, MICRONIZED ORGANIC UV-SCREENING AGENT INSOLUBLE THEREIN, MEAN PARTICLE SIZE OF MICRONIZED PARTICLES BEING 0.01-2 MU M, OPTIONALLY, CROSSLINKED POLYMER OF ETHYLENICALLY UNSATURATED MONOMER SOCIETE L'OREAL (FR) 2002-07-09 US claimed
WO-2002049597-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2002-06-27 WO claimed
US-6409998-B1 UV-photoprotecting emulsions comprising micronized insoluble screening agents and associative polymers SOCIETE L'OREAL (FR) 2002-06-25 US claimed
US-6403061-B1 TOPICAL APPLYING PROTECTIVE PHOTOSENSITIVE COATING SOCIETE L'OREAL (FR) 2002-06-11 US claimed
EP-1093797-B1 Process for the photostabilisation of sunscreens derived from dibenzoylmethane by an insoluble organic filter OREAL (FR) 2002-02-20 EP claimed
EP-1093797-A1 Process for the photostabilisation of sunscreens derived from dibenzoylmethane by an insoluble organic filter L'OREAL (FR) 2001-04-25 EP claimed
EP-1093798-A1 Emulsions without emulsifiers containing at least one insoluble organic UV-filter L'OREAL (FR) 2001-04-25 EP claimed
EP-1093799-A1 Water-in-Oil emulsions containing at least one insoluble organic UV filter and a non-filtrating organomodified silicone L'OREAL (FR) 2001-04-25 EP claimed
EP-1093796-A1 Emulsions containing one or more insoluble organic UV-filter and an associative polymer L'OREAL (FR) 2001-04-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, DSG1, PCNA EPHX1 1447/4885ZDHHC20 1587/4885ZDHHC2 1406/4885
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SUCLG1, CUTA, DLD EPHX1 2215/4885ZDHHC20 2479/4885ZDHHC2 2014/4885
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS HADHB, SDHA, ERCC4 EPHX1 3530/4885ZDHHC20 2419/4885ZDHHC2 2342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.