Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | SI | P14410 | 1/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823055 | 0.82 | ALDH1A1 (0.36) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL28838395 | 0.79 | IDO1 (0.45) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL30314645 | 0.77 | ALDH1A1 (0.50) | RAB9AALDH1A1KDM4EHSD11B1NPC1 | |
| SCHEMBL7146697 | 0.72 | FBP1 (0.47) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL8859981 | 0.70 | FBP1 (0.49) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL31264268 | 0.70 | NOTUM (0.46) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL29624840 | 0.70 | AHR (0.64) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL464507 | 0.70 | AHR (0.64) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL3434993 | 0.69 | ALDH1A1 (1.00) | RAB9AALDH1A1KDM4EGAAMGAM | |
| SCHEMBL22816341 | 0.69 | SHMT1 (0.49) | RAB9AALDH1A1KDM4EGAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240343717-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343717-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | NOX1, CASP1, CYP51A1 | RAB9A 1637/4885ALDH1A1 533/4885KDM4E 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.