Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996666 | 0.84 | PDE2A (0.41) | NPC1RAB9AHSD17B10PKMCREBBP | |
| SCHEMBL19369166 | 0.81 | RAB9A (0.43) | TP53KDM4ENPC1RAB9AGAA | |
| SCHEMBL27037461 | 0.81 | PDE2A (0.43) | ALDH1A1KDM4ENPC1RAB9ACREBBP | |
| SCHEMBL21051439 | 0.81 | NPC1 (0.42) | ALDH1A1TP53KDM4ENPC1RAB9A | |
| SCHEMBL12856337 | 0.81 | PDE2A (0.43) | ALDH1A1TP53NPC1RAB9ACREBBP | |
| SCHEMBL15745978 | 0.80 | CYP1A1 (0.44) | CREBBPBRD4MAPTPTGS2PDE2A | |
| SCHEMBL18985744 | 0.80 | TDP1 (0.43) | ALDH1A1TP53KDM4ENPC1RAB9A | |
| SCHEMBL30230864 | 0.80 | NOS3 (0.42) | ALDH1A1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL9911757 | 0.80 | PTGS2 (0.46) | ALDH1A1KDM4ENPC1RAB9ACREBBP | |
| SCHEMBL31306253 | 0.79 | KEAP1 (0.39) | ALDH1A1TP53KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4734979-A2 | TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006723-A2 | TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2025-01-02 | — | — | WO | disclosed |