Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19149984 | 0.71 | ALDH1A1 (0.38) | MEN1KMT2ASIGMAR1NPC1RAB9A | |
| SCHEMBL7992349 | 0.71 | CHRNB2 (0.46) | ALDH1A1CHRNA7CYP3A4CHRNB2MAPK1 | |
| SCHEMBL15574255 | 0.68 | LMNA (0.55) | MEN1KMT2ASIGMAR1NPC1RAB9A | |
| SCHEMBL21159576 | 0.65 | ALDH1A1 (0.42) | MEN1KMT2ASIGMAR1NPC1RAB9A | |
| SCHEMBL15416152 | 0.63 | — | — | |
| SCHEMBL25001981 | 0.63 | SIGMAR1 (0.50) | MEN1KMT2ASIGMAR1NPC1RAB9A | |
| SCHEMBL4913801 | 0.62 | LMNA (0.43) | MEN1KMT2ASIGMAR1NPC1RAB9A | |
| SCHEMBL8667665 | 0.62 | BPTF (0.39) | MEN1KMT2ASIGMAR1NPC1RAB9A | |
| SCHEMBL18228234 | 0.62 | L3MBTL1 (0.61) | MEN1KMT2ASIGMAR1NPC1RAB9A | |
| SCHEMBL16924863 | 0.62 | LMNA (0.61) | MEN1KMT2ASIGMAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119156382-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-17 | — | — | CN | disclosed |