Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31316911 | 0.84 | TP53 (0.54) | L3MBTL1F2PLAUKLKB1ELANE | |
| SCHEMBL31316899 | 0.84 | F2 (0.45) | L3MBTL1F2PLAUKLKB1ELANE | |
| SCHEMBL31316890 | 0.84 | F2 (0.45) | L3MBTL1F2PLAUKLKB1ELANE | |
| SCHEMBL31316910 | 0.82 | F2 (0.50) | F2PLAUKLKB1ELANEMEN1 | |
| SCHEMBL31316781 | 0.81 | ALDH1A1 (0.45) | L3MBTL1F2PLAUKLKB1ELANE | |
| SCHEMBL7114840 | 0.80 | F2 (0.53) | L3MBTL1F2PLAUKLKB1ELANE | |
| SCHEMBL4134448 | 0.77 | L3MBTL1 (0.55) | L3MBTL1MEN1KMT2APOLBKDM4E | |
| SCHEMBL31316906 | 0.76 | LMNA (0.56) | L3MBTL1KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL182136 | 0.75 | KEAP1 (0.51) | L3MBTL1KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL16062208 | 0.75 | TP53 (0.49) | KEAP1NFE2L2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743453-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | Pretzel Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015178-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |