Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | KIF18A | Q8NI77 | 14/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24213988 | 0.84 | PTGER4 (0.55) | PTGER4KIF18AGBA1NAPEPLD | |
| SCHEMBL31320212 | 0.83 | TDP1 (0.44) | WNT1GSK3BDYRK1ACLK2CLK3 | |
| SCHEMBL31320165 | 0.83 | PTGER4 (0.44) | PTGER4KIF18AGBA1WNT1GSK3B | |
| SCHEMBL30615976 | 0.80 | KIF18A (0.45) | PTGER4KIF18ANAPEPLD | |
| SCHEMBL30600624 | 0.77 | KIF18A (0.51) | KIF18A | |
| SCHEMBL26646308 | 0.77 | KIF18A (0.51) | KIF18A | |
| SCHEMBL31320154 | 0.75 | SCN10A (0.47) | KIF18ASCN10A | |
| SCHEMBL24213932 | 0.75 | PTGER4 (0.39) | PTGER4KIF18AGBA1WNT1GSK3B | |
| SCHEMBL22148686 | 0.75 | GRIN2D (0.50) | PTGER4KIF18AGBA1 | |
| SCHEMBL22288959 | 0.74 | ALDH1A1 (0.41) | PTGER4KIF18AGSK3BSCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250264-A1 | KIF18A INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2025-08-07 | — | — | US | disclosed |
| EP-4509505-A1 | KIF18A INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2025-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250250264-A1 | KIF18A INHIBITOR AND USE THEREOF | KIF18A, KIF18B, KIF15 | PTGER4 4639/4885KIF18A 1/4885GBA1 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.