Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | WHR1 | P49842 | 1/20 | 0.37 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24213988 | 0.85 | PTGER4 (0.55) | PTGER4GBA1PIK3CAKIF18AKDM4E | |
| SCHEMBL31320141 | 0.83 | PTGER4 (0.46) | PTGER4GBA1KIF18ANAPEPLDWNT1 | |
| SCHEMBL19367477 | 0.81 | PIK3CA (0.60) | PIK3CAPIK3CBALDH1A1KMT2AMEN1 | |
| SCHEMBL30615828 | 0.79 | KIF18A (0.43) | PTGER4GBA1KIF18ACRBNNAPEPLD | |
| SCHEMBL475674 | 0.77 | ALDH1A1 (0.43) | KDM4EALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL26646283 | 0.76 | RBP4 (0.58) | KIF18AKCNQ3KCNQ2KDM4EALDH1A1 | |
| SCHEMBL30600681 | 0.76 | RBP4 (0.58) | KIF18AKCNQ3KCNQ2KDM4EALDH1A1 | |
| SCHEMBL27457591 | 0.75 | GBA1 (0.47) | PTGER4GBA1KIF18AKDM4EALDH1A1 | |
| SCHEMBL19995500 | 0.75 | PRKD1 (0.44) | PIK3CAPIK3CBCRBNKDM4EALDH1A1 | |
| SCHEMBL31320279 | 0.74 | KIF18A (0.45) | KIF18AKCNQ3KCNQ2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250264-A1 | KIF18A INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2025-08-07 | — | — | US | disclosed |
| EP-4509505-A1 | KIF18A INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2025-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250250264-A1 | KIF18A INHIBITOR AND USE THEREOF | KIF18A, KIF18B, KIF15 | PTGER4 4639/4885GBA1 1587/4885PIK3CA 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.