Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13621786 | 0.87 | HDAC3 (0.36) | ESR1ESR2 | |
| SCHEMBL31322158 | 0.87 | HCRTR2 (0.37) | ESR1ESR2OPRK1 | |
| SCHEMBL31322144 | 0.87 | HTR6 (0.48) | ESR1ESR2OPRK1 | |
| SCHEMBL31322157 | 0.83 | L3MBTL1 (0.44) | — | |
| SCHEMBL13632640 | 0.83 | SIRT2 (0.43) | — | |
| SCHEMBL31322118 | 0.81 | CCR5 (0.39) | — | |
| SCHEMBL16071303 | 0.80 | DNM1 (0.33) | ESR1ESR2 | |
| SCHEMBL13361987 | 0.69 | LMNA (0.44) | ESR2ADRA1AOPRK1 | |
| SCHEMBL30099079 | 0.66 | NOTUM (0.41) | — | |
| SCHEMBL31322121 | 0.65 | CRBN (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4483866-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF CANCER | Makrolife Biotech GmbH (DE) | 2025-01-01 | — | — | EP | claimed |
| EP-4483866-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF CANCER | Makrolife Biotech GmbH (DE) | 2025-01-01 | — | — | EP | disclosed |