Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31322148 | 0.87 | ESR1 (0.47) | ESR1ESR2OPRK1 | |
| SCHEMBL13621786 | 0.86 | HDAC3 (0.36) | MEN1KMT2APOLBESR1ESR2 | |
| SCHEMBL31322144 | 0.86 | HTR6 (0.48) | MEN1KMT2AESR1ESR2GSK3B | |
| SCHEMBL31322118 | 0.83 | CCR5 (0.39) | — | |
| SCHEMBL13632640 | 0.82 | SIRT2 (0.43) | LMNAPOLB | |
| SCHEMBL31322157 | 0.82 | L3MBTL1 (0.44) | L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL31322121 | 0.78 | CRBN (0.41) | MEN1KMT2ALMNAALDH1A1CYP2C19 | |
| SCHEMBL13361987 | 0.70 | LMNA (0.44) | LMNAALDH1A1ESR2MAPTOPRK1 | |
| SCHEMBL5870956 | 0.67 | SIRT2 (0.47) | ALDH1A1 | |
| SCHEMBL12049115 | 0.66 | OPRK1 (0.35) | MEN1KMT2AOPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4483866-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF CANCER | Makrolife Biotech GmbH (DE) | 2025-01-01 | — | — | EP | claimed |
| EP-4483866-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF CANCER | Makrolife Biotech GmbH (DE) | 2025-01-01 | — | — | EP | disclosed |