Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13233215 | 0.88 | NCEH1 (0.48) | NCEH1ERN1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL1414936 | 0.85 | ERN1 (0.51) | NCEH1ERN1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL7245579 | 0.82 | CYP2A6 (0.38) | LMNAHTR1AHTR1DHTR1BEPAS1 | |
| SCHEMBL3133132 | 0.82 | ACHE (0.36) | NCEH1ERN1RXFP1CYP2A6CA1 | |
| SCHEMBL31456219 | 0.81 | HSD11B1 (0.45) | NCEH1LMNASMN1; SMN2L3MBTL1HTR1A | |
| SCHEMBL1195896 | 0.81 | HSD11B1 (0.45) | NCEH1LMNASMN1; SMN2L3MBTL1HTR1A | |
| SCHEMBL1304036 | 0.80 | ESR1 (0.43) | HSD17B1HSD17B2CA1CA2 | |
| SCHEMBL6700942 | 0.79 | PDE4A (0.42) | NCEH1EPAS1HSD11B1CA1CA2 | |
| SCHEMBL29560409 | 0.78 | MAPT (0.49) | SMN1; SMN2L3MBTL1HTR1AHTR1DHTR1B | |
| SCHEMBL635407 | 0.78 | MAPT (0.49) | SMN1; SMN2L3MBTL1HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-01-11 | — | — | US | disclosed |
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-01-11 | — | — | US | disclosed |
| US-20040102649-A1 | Water soluble chiral diphoshpines | RHODIA CHIMIE (FR) | 2004-05-27 | — | — | US | disclosed |
| US-20030225297-A1 | Process for preparing chiral diphosphines | RHODIA CHIMIE | 2003-12-04 | — | — | US | disclosed |
| US-6646106-B1 | Polymerizing chiral diphosphine having a C2 axis of symmetry, with one or several polymerizable monomers, said chiral diphosphine consisting of a chiral body bearing two identical functional groups | RHODIA CHIMIE (FR) | 2003-11-11 | — | — | US | disclosed |
| US-6610875-B1 | Forming bidentate ligands ofr assymetric catalysts; bromina-ting diaryldiol; esterifying with sulfonic acid; substituting cyano for bromine groups; coupling with a dicyclophosphine | RHODIA CHIMIE (FR) | 2003-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102649-A1 | Water soluble chiral diphoshpines | ADRA1B, ADRB1, ADRA1A | NCEH1 656/4885ERN1 4015/4885RXFP1 283/4885 |
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | MPI, ITPA, DCPS | NCEH1 3192/4885ERN1 3426/4885RXFP1 4842/4885 |
| US-20030225297-A1 | Process for preparing chiral diphosphines | CYP1A1, NR5A1, AR | NCEH1 1263/4885ERN1 1054/4885RXFP1 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.