Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.48 |
| ▸ | LPO | P22079 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | GRK5 | P34947 | 1/20 | 0.46 |
| ▸ | GRK6 | P43250 | 1/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.46 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.46 |
| ▸ | GRK7 | Q8WTQ7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16861414 | 0.86 | MEN1 (0.48) | TP53LMNAMAPTCMA1ROCK2 | |
| SCHEMBL31333025 | 0.84 | ALDH1A1 (0.51) | TP53ADRA1DLMNAMAPTALDH1A1 | |
| SCHEMBL31333022 | 0.81 | ROCK2 (0.44) | MAPTROCK2ROCK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7984239 | 0.81 | ADRA1D (0.52) | TP53RXFP1ADRA1DLMNAMAPT | |
| SCHEMBL16861507 | 0.79 | HTT (0.49) | LMNAROCK2GRK2ALDH1A1MEN1 | |
| SCHEMBL31333086 | 0.78 | ATM (0.51) | TP53RXFP1LMNAMAPTROCK2 | |
| SCHEMBL7992368 | 0.77 | TP53 (0.47) | TP53RXFP1ADRA1DMAPTLPO | |
| SCHEMBL31333017 | 0.77 | TP53 (0.45) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL31333059 | 0.77 | PDE5A (0.47) | TP53LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL31333091 | 0.76 | ADRA1D (0.51) | ADRA1DLMNAALDH1A1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320386-A | METTL3 inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2025-01-17 | — | — | CN | disclosed |