Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LPO | P22079 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987961 | 0.86 | MAPT (0.47) | TP53RXFP1ADRA1DYTHDC1NR3C2 | |
| SCHEMBL7985340 | 0.86 | NTRK1 (0.51) | ADRA1DMAPTMEN1KMT2ARAB9A | |
| SCHEMBL7985670 | 0.85 | CDK9 (0.42) | YTHDC1NR3C2MAPTKMT2AMAPK8 | |
| SCHEMBL7974162 | 0.85 | KDM4E (0.52) | TP53RXFP1ADRA1DYTHDC1MAPT | |
| SCHEMBL7985508 | 0.85 | ALDH1A1 (0.43) | MEN1KMT2A | |
| SCHEMBL7991565 | 0.84 | TSHR (0.49) | ADRA1DYTHDC1KMT2A | |
| SCHEMBL7986281 | 0.83 | KMT2A (0.39) | MTNR1AMTNR1BYTHDC1MAPTKMT2A | |
| SCHEMBL7987598 | 0.83 | RIOK2 (0.41) | YTHDC1MEN1KMT2AMAPK8RAB9A | |
| SCHEMBL7974433 | 0.83 | TP53 (0.40) | TP53RXFP1ADRA1DYTHDC1PTGER3 | |
| SCHEMBL7988637 | 0.82 | NPC1 (0.51) | TP53ADRA1DYTHDC1PTGER3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |