Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333022 | 0.84 | ROCK2 (0.44) | ROCK2ROCK1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31333025 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2MAPTLMNA | |
| SCHEMBL7974034 | 0.81 | ATM (0.48) | ATMROCK2ROCK1ALDH1A1KDM4E | |
| SCHEMBL31333074 | 0.78 | TP53 (0.53) | ROCK2ROCK1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31333078 | 0.77 | GRM2 (0.47) | KDM4ESMN1; SMN2MAPTKCNH2LMNA | |
| SCHEMBL31333054 | 0.77 | ALDH1A1 (0.47) | ATMALDH1A1KDM4EMAOBNR3C2 | |
| SCHEMBL31333091 | 0.76 | ADRA1D (0.51) | ALDH1A1KDM4ESMN1; SMN2LMNAHSD17B13 | |
| SCHEMBL31333084 | 0.76 | CA5A (0.52) | ROCK2KCNH2KDM4C | |
| SCHEMBL27645551 | 0.75 | ATM (0.50) | ATMALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL31333071 | 0.75 | CCNC (0.45) | ALDH1A1KDM4ERXFP1HSD17B13KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320386-A | METTL3 inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2025-01-17 | — | — | CN | disclosed |