Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 14/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334881 | 0.87 | SIRT6 (0.48) | SIRT6MAPTTHRBPKMALDH1A1 | |
| SCHEMBL31333435 | 0.83 | MAPT (0.55) | SIRT6MAPTTHRBPKMALDH1A1 | |
| SCHEMBL31333248 | 0.81 | MAPT (0.55) | SIRT6MAPTTHRBPKMALDH1A1 | |
| SCHEMBL31333447 | 0.81 | DRD2 (0.47) | SIRT6MAPTTHRBPKMALDH1A1 | |
| SCHEMBL23538376 | 0.79 | MEN1 (0.43) | SIRT6MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL29744877 | 0.79 | MEN1 (0.43) | SIRT6MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14406629 | 0.77 | MAPT (0.56) | SIRT6MAPTTHRBPKMALDH1A1 | |
| SCHEMBL31333569 | 0.76 | ENPP2 (0.38) | — | |
| SCHEMBL25173075 | 0.76 | MAPT (0.60) | SIRT6MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL31334467 | 0.75 | SIRT6 (0.50) | SIRT6MAPTTHRBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |