Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 15/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333610 | 0.85 | SIRT6 (0.51) | SIRT6MAPTALDH1A1THRBPKM | |
| SCHEMBL26495684 | 0.81 | ALDH1A1 (0.52) | SIRT6MAPTALDH1A1TP53HTT | |
| SCHEMBL30497535 | 0.81 | ALDH1A1 (0.52) | SIRT6MAPTALDH1A1TP53HTT | |
| SCHEMBL31334881 | 0.80 | SIRT6 (0.48) | SIRT6MAPTALDH1A1THRBPKM | |
| SCHEMBL31333435 | 0.79 | MAPT (0.55) | SIRT6MAPTALDH1A1THRBPKM | |
| SCHEMBL31333447 | 0.78 | DRD2 (0.47) | SIRT6MAPTALDH1A1THRBPKM | |
| SCHEMBL31333430 | 0.78 | MAPT (0.51) | MAPTALDH1A1THRBHTTDRD2 | |
| SCHEMBL4516920 | 0.78 | MAPT (0.56) | SIRT6MAPTALDH1A1DRD2GALR3 | |
| SCHEMBL30919620 | 0.77 | MAPT (0.63) | MAPTALDH1A1HTTTDP1GALR3 | |
| SCHEMBL30258576 | 0.77 | MAPT (0.60) | MAPTALDH1A1HTTTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |