Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.42 |
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 6/20 | 0.36 |
| ▸ | RARA | P10276 | 5/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25155975 | 0.81 | RXRA (0.43) | RXRARARBARRARGRARA | |
| SCHEMBL30701833 | 0.74 | RXRA (0.69) | RXRARARBRARGRARARXRB | |
| SCHEMBL7149480 | 0.74 | RXRA (0.69) | RXRARARBRARGRARARXRB | |
| SCHEMBL31456579 | 0.72 | RARB (0.53) | RXRARARBRARGRARAALDH1A1 | |
| SCHEMBL31335589 | 0.72 | ATAD2 (0.42) | RXRARARBCSNK2A1CA12CA1 | |
| SCHEMBL31335591 | 0.72 | ATAD2 (0.42) | RXRARARBCSNK2A1CA12CA1 | |
| SCHEMBL21026575 | 0.71 | RXRA (0.45) | RXRARARBRARGRARACSNK2A1 | |
| SCHEMBL31335734 | 0.70 | GAA (0.42) | RXRARARBARRARGRARA | |
| SCHEMBL25156171 | 0.68 | MAPT (0.39) | RXRARARBARRARGRARA | |
| SCHEMBL10828177 | 0.67 | MRGPRX2 (0.37) | RARBARRARGALDH1A1CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |