SCHEMBL3134441

SCHEMBL3134441

Cc1ccccc1S(OS(=O)(=O)c1ccc(C(F)(F)F)cc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 11/20 0.49
MCL1 Q07820 1/20 0.41
PTGES2 Q9H7Z7 1/20 0.39
ABCC9 O60706 1/20 0.38
ABCC8 Q09428 1/20 0.38
KCNJ11 Q14654 1/20 0.38
KCNJ8 Q15842 1/20 0.38
IDH1 O75874 2/20 0.38
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
PTGS2 P35354 2/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
HTT P42858 1/20 0.37
PTGS1 P23219 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3201722 0.87 MCL1 (0.43) HSD11B1MCL1ABCC9ABCC8KCNJ11
SCHEMBL6761853 0.87 HTR6 (0.40) HSD11B1LMNAPOLBHTT
SCHEMBL3203657 0.86 HSD11B1 (0.40) HSD11B1BCHEACHEPTGS2LMNA
SCHEMBL3132687 0.85 HSD11B1 (0.45) HSD11B1PTGES2PTGS2LMNAPOLB
SCHEMBL3139775 0.85 HSD11B1 (0.45) HSD11B1PTGES2PTGS2LMNAPOLB
SCHEMBL503702 0.85 HSD11B1 (0.45) HSD11B1PTGES2PTGS2LMNAPOLB
SCHEMBL3134871 0.85 HSD11B1 (0.47) HSD11B1PTGES2PTGS2
SCHEMBL3134802 0.85 HSD11B1 (0.47) HSD11B1PTGES2PTGS2
SCHEMBL3136577 0.85 BCHE (0.49) HSD11B1BCHEACHEPTGS2HTT
SCHEMBL3132919 0.85 BCHE (0.49) HSD11B1BCHEACHEPTGS2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 HSD11B1 718/4885MCL1 2666/4885PTGES2 3234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.