Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5122215 | 0.79 | HTT (0.57) | TSHRGAAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31347379 | 0.79 | KMT2A (0.54) | TP53ALDH1A1KMT2AMAPT | |
| SCHEMBL31347381 | 0.79 | LMNA (0.52) | TP53ALDH1A1LMNAPOLB | |
| SCHEMBL31347385 | 0.79 | EGLN1 (0.61) | KMT2AMMP13 | |
| SCHEMBL5121092 | 0.78 | LMNA (0.66) | TSHRTP53GAAALDH1A1NPSR1 | |
| SCHEMBL31347377 | 0.78 | ALDH1A1 (0.55) | TSHRGAAALDH1A1KMT2ALMNA | |
| SCHEMBL5114509 | 0.78 | EGLN1 (0.58) | ALDH1A1HTTPOLB | |
| SCHEMBL31347376 | 0.78 | KMT2A (0.46) | ALDH1A1KMT2A | |
| SCHEMBL31347378 | 0.77 | MMP13 (0.58) | TP53ALDH1A1CYP3A4CYP2C9HTT | |
| SCHEMBL31347370 | 0.76 | MLYCD (0.57) | GAACYP1A2CYP3A4KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371360-A | 5, 6-Dihydroxypyrimidine compound and preparation method and application thereof | 暨南大学 | 2025-01-28 | — | — | CN | disclosed |