Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.61 |
| ▸ | MMP13 | P45452 | 5/20 | 0.54 |
| ▸ | MMP3 | P08254 | 4/20 | 0.54 |
| ▸ | MMP1 | P03956 | 4/20 | 0.54 |
| ▸ | MMP7 | P09237 | 4/20 | 0.54 |
| ▸ | MMP9 | P14780 | 4/20 | 0.54 |
| ▸ | MMP8 | P22894 | 4/20 | 0.54 |
| ▸ | MMP12 | P39900 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114509 | 0.84 | EGLN1 (0.58) | EGLN1 | |
| SCHEMBL31347376 | 0.84 | KMT2A (0.46) | EGLN1HDAC1MEN1KMT2A | |
| SCHEMBL31347377 | 0.84 | ALDH1A1 (0.55) | EGLN1RAB9AMEN1KMT2A | |
| SCHEMBL31347382 | 0.82 | SMN1; SMN2 (0.51) | EGLN1HDAC1NPC1RAB9AMEN1 | |
| SCHEMBL31347380 | 0.81 | MMP2 (0.52) | EGLN1MMP3MMP2EPHX2HDAC1 | |
| SCHEMBL5113449 | 0.80 | HPGDS (0.56) | MMP13EPHX2NR1H4HDAC4HDAC6 | |
| SCHEMBL5114522 | 0.80 | SMN1; SMN2 (0.49) | MEN1KMT2A | |
| SCHEMBL31347374 | 0.79 | TSHR (0.56) | MMP13KMT2A | |
| SCHEMBL31347381 | 0.78 | LMNA (0.52) | EGLN1 | |
| SCHEMBL31347379 | 0.78 | KMT2A (0.54) | NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371360-A | 5, 6-Dihydroxypyrimidine compound and preparation method and application thereof | 暨南大学 | 2025-01-28 | — | — | CN | disclosed |