SCHEMBL3134874

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2853714	0.86	MAPT (0.52)	MEN1KMT2ALMNAUSP2KDM4E
	SCHEMBL23797957	0.84	KEAP1 (0.49)	MEN1KMT2ALMNAUSP2KDM4E
	SCHEMBL1797972	0.82	HSPB1 (0.54)	LMNAKDM4EHSPB1MAPTMAPK1
	SCHEMBL1589066	0.79	LMNA (0.65)	MEN1KMT2ALMNAKDM4EALDH1A1
	SCHEMBL23361431	0.78	LMNA (0.44)	LMNAKDM4EALOX5APFEN1HSPB1
	SCHEMBL23361514	0.78	ALDH1A1 (0.48)	MEN1KMT2ALMNAKDM4EALDH1A1
	SCHEMBL4314966	0.78	MEN1 (0.53)	MEN1KMT2AKDM4EKEAP1ALOX5AP
	SCHEMBL3640462	0.77	KDM4E (0.64)	MEN1KMT2ALMNAKDM4EALDH1A1
	SCHEMBL15921050	0.77	MEN1 (0.71)	MEN1KMT2AKDM4EALDH1A1HSD17B10
	SCHEMBL12469040	0.76	MEN1 (0.51)	MEN1KMT2ALMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.