Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CPB1 | P15086 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31350686 | 0.88 | CPB1 (0.47) | CTSBCTSKCTSLCPB1ALDH1A1 | |
| SCHEMBL4376239 | 0.87 | CTSK (0.48) | CTSBCTSKCTSSCTSLCPB1 | |
| SCHEMBL31350488 | 0.83 | CTSK (0.53) | CTSBCTSKCTSLCPB1ALDH1A1 | |
| SCHEMBL2535872 | 0.82 | PDE4B (0.47) | CTSBCTSKCTSSCTSLCPB1 | |
| SCHEMBL14820339 | 0.79 | ALDH1A1 (0.62) | CTSBCTSKCTSLCPB1ALDH1A1 | |
| SCHEMBL19013539 | 0.78 | ALDH1A1 (0.53) | CTSBCTSKCTSLCPB1ALDH1A1 | |
| SCHEMBL17764587 | 0.78 | CTSB (0.57) | CTSBCTSKCTSSCTSLCPB1 | |
| SCHEMBL17764588 | 0.78 | CTSB (0.57) | CTSBCTSKCTSSCTSLCPB1 | |
| SCHEMBL21344554 | 0.77 | CTSK (0.52) | CTSBCTSKCTSLCPB1ALDH1A1 | |
| SCHEMBL10450033 | 0.75 | ALDH1A1 (0.56) | CTSBCTSKCTSLCPB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743462-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012643-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2025-01-16 | — | — | WO | disclosed |