Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CPB1 | P15086 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2535872 | 0.87 | PDE4B (0.47) | CTSKCTSBCTSSCTSLCPB1 | |
| SCHEMBL31350554 | 0.87 | CTSB (0.48) | CTSKCTSBCTSSCTSLCPB1 | |
| SCHEMBL28670342 | 0.84 | CPB1 (0.46) | CTSKCTSBCTSLCPB1ALDH1A1 | |
| SCHEMBL20479939 | 0.84 | CPB1 (0.46) | CTSKCTSBCTSLCPB1ALDH1A1 | |
| SCHEMBL4374791 | 0.84 | CPB1 (0.46) | CTSKCTSBCTSLCPB1ALDH1A1 | |
| SCHEMBL23931103 | 0.82 | CPB1 (0.50) | CTSKCTSBCTSLCPB1ALDH1A1 | |
| SCHEMBL4366638 | 0.82 | CTSK (0.58) | CTSKCTSBCTSLCPB1ALDH1A1 | |
| SCHEMBL4364990 | 0.82 | CTSK (0.58) | CTSKCTSBCTSLCPB1ALDH1A1 | |
| SCHEMBL20479723 | 0.82 | ALDH1A1 (0.53) | CTSKCTSBCTSLCPB1ALDH1A1 | |
| SCHEMBL18342179 | 0.82 | ALDH1A1 (0.53) | CTSKCTSBCTSLCPB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291940-A1 | AMINOPYRROLIDINE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-11-26 | — | — | US | disclosed |
| EP-2003131-A1 | AMINOPYRROLIDINE COMPOUND | Taisho Pharmaceutical Co. Ltd. (JP) | 2008-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291940-A1 | AMINOPYRROLIDINE COMPOUND | MC4R, MC5R, MC2R | CTSK 4712/4885CTSB 4437/4885CTSS 4620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.