Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793810 | 0.78 | GPR17 (0.60) | GPR17METAP2TUBB4ATUBBTUBA3C | |
| SCHEMBL4895906 | 0.78 | KDM4E (0.72) | KDM4ETDP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25738484 | 0.76 | METAP2 (0.47) | KDM4EMETAP2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL18481324 | 0.74 | ALDH1A1 (0.50) | PRNPCYP1A2CYP2C9CYP2C19PPARG | |
| SCHEMBL31422791 | 0.73 | GABRA1 (0.49) | KDM4EALDH1A1HTT | |
| SCHEMBL8889498 | 0.73 | KEAP1 (0.50) | KDM4ETDP1CYP2C19ALDH1A1HTT | |
| SCHEMBL2372152 | 0.73 | LMNA (0.51) | KDM4ECYP1A2RXFP1ALDH1A1MEN1 | |
| SCHEMBL19180001 | 0.72 | RHEB (0.43) | GPR17KDM4ETDP1TUBB4ATUBB | |
| SCHEMBL17433380 | 0.72 | RHEB (0.43) | GPR17KDM4ETDP1TUBB4ATUBB | |
| SCHEMBL3985035 | 0.71 | GSK3B (0.54) | KDM4ETDP1PRNPCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143752-A | Aminoquinoline derivative, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-12-17 | — | — | CN | disclosed |