SCHEMBL31359442

SCHEMBL31359442

C[n+]1cn([C@@H]2O[C@H](CO)[C@](O)(OS(C)(=O)=O)[C@H]2O)c2nc(N)[nH]c(=O)c21

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PNP P00491 3/20 0.35
▸ HINT1 P49773 4/20 0.33
▸ TLR7 Q9NYK1 4/20 0.33
▸ HPGD P15428 1/20 0.33
▸ NT5E P21589 1/20 0.33
▸ APOBEC3G Q9HC16 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30579774 0.85 TGM2 (0.39) PNPNT5E
SCHEMBL31483545 0.83 HINT1 (0.37) HINT1NT5E
SCHEMBL31483544 0.81 HINT1 (0.37) HINT1NT5E
SCHEMBL30579769 0.81 POLB (0.36) HINT1NT5E
SCHEMBL12959076 0.77 PNP (0.56) PNPHINT1TLR7HPGDMEN1
SCHEMBL12820927 0.77 PNP (0.56) PNPHINT1TLR7HPGDMEN1
SCHEMBL40998 0.77 PNP (0.56) PNPHINT1TLR7HPGDMEN1
SCHEMBL30326363 0.76 PNP (0.55) PNPHINT1TLR7HPGDMEN1
SCHEMBL31726147 0.75 TLR7 (0.48) PNPTLR7
SCHEMBL26568527 0.75 PNP (0.40) PNPHINT1TLR7NT5EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12522630-B2 MRNA cap analog and uses thereof HANMI FINE CHEMICAL CO., LTD. (KR) 2026-01-13 — — US disclosed
US-20250230183-A1 MRNA CAP ANALOG AND USES THEREOF HANMI FINE CHEMICAL CO., LTD. (KR) 2025-07-17 — — US disclosed
EP-4506353-A1 MRNA CAP ANALOG AND USES THEREOF Hanmi Fine Chemical Co., Ltd. (KR) 2025-02-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230183-A1 MRNA CAP ANALOG AND USES THEREOF RNGTT, RNMT, CAP1 PNP 635/4885HINT1 579/4885TLR7 2605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback