Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | MYLK | Q15746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648491 | 0.87 | IDO1 (0.44) | PDK2IDO1MEN1ALDH1A1HTT | |
| SCHEMBL6643892 | 0.80 | TSHR (0.42) | IDO1TSHRTAAR1 | |
| SCHEMBL29712515 | 0.79 | HSPA5 (0.45) | IDO1TSHRTAAR1 | |
| SCHEMBL1538555 | 0.79 | HSPA5 (0.45) | IDO1TSHRTAAR1 | |
| SCHEMBL8459673 | 0.78 | GABRA1 (0.42) | PDK2IDO1ALDH1A1HTTNPSR1 | |
| SCHEMBL23480864 | 0.76 | IDO1 (0.63) | IDO1 | |
| SCHEMBL4979415 | 0.76 | ALDH1A1 (0.38) | PDK2IDO1MEN1ALDH1A1HTT | |
| SCHEMBL22711438 | 0.76 | IDO1 (0.40) | PDK2IDO1MEN1ALDH1A1HTT | |
| SCHEMBL18055973 | 0.76 | IDO1 (0.40) | PDK2IDO1MEN1ALDH1A1HTT | |
| SCHEMBL155804 | 0.76 | IDO1 (0.61) | IDO1ALDH1A1HTTKCNN4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555257-B1 | PROCESS FOR PRODUCING AROMATIC NITRILE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2010-01-20 | — | — | EP | disclosed |
| EP-1661877-B1 | PROCESS FOR PRODUCING AROMATIC ALDEHYDE | IHARA CHEMICAL IND CO (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-7342138-B2 | Process for producing aromatic aldehyde | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-03-11 | — | — | US | disclosed |
| US-7262316-B2 | Process for producing aromatic nitrile compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20070004934-A1 | Process for producing aromatic aldehyde | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1661877-A1 | PROCESS FOR PRODUCING AROMATIC ALDEHYDE | Ihara Chemical Industry Co., Ltd. (JP) | 2006-05-31 | — | — | EP | disclosed |
| US-20060069282-A1 | Process for producing aromatic nitrile compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-03-30 | — | — | US | disclosed |
| EP-1555257-A1 | PROCESS FOR PRODUCING AROMATIC NITRILE COMPOUND | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2005-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069282-A1 | Process for producing aromatic nitrile compound | ODC1, ALKBH3, GNMT | PDK2 762/4885IDO1 988/4885MEN1 1824/4885 |
| US-20070004934-A1 | Process for producing aromatic aldehyde | ALKBH3, AOX1, ALDH3A1 | PDK2 190/4885IDO1 711/4885MEN1 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.