SCHEMBL313678

SCHEMBL313678

COC(=O)COC(=O)C(Cc1ccc(OC(C(=O)OC)C(=O)OC)cc1)NC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
TACR1 P25103 3/20 0.44
ACACB O00763 7/20 0.42
ITGB3 P05106 1/20 0.42
ITGA2B P08514 1/20 0.42
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
KMT2A Q03164 1/20 0.40
PPARG P37231 1/20 0.40
GAA P10253 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313085 0.86 ITGB3 (0.50) TACR1ACACBITGB3ITGA2BMEN1
SCHEMBL313677 0.84 ITGB3 (0.48) TACR1ACACBITGB3ITGA2BMEN1
SCHEMBL313634 0.83 TACR1 (0.51) TSHRTACR1ALDH1A1KMT2A
SCHEMBL313030 0.82 MEN1 (0.54) TSHRACACBITGB3ITGA2BMEN1
SCHEMBL1857477 0.78 ALDH1A1 (0.50) TSHRACACBITGB3ITGA2BMEN1
SCHEMBL5706152 0.77 ACACB (0.58) TSHRTACR1ACACBITGB3ITGA2B
SCHEMBL6662892 0.77 ACACB (0.58) TSHRTACR1ACACBITGB3ITGA2B
SCHEMBL863032 0.75 KMT2A (0.51) TSHRTACR1ACACBITGB3ITGA2B
SCHEMBL5887308 0.74 ATM (0.50) TSHRTACR1ALDH1A1LMNAKMT2A
SCHEMBL2520016 0.74 ATM (0.50) TSHRTACR1ALDH1A1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
EP-1948713-B1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2013-12-04 EP disclosed
US-20130317118-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-11-28 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-01-31 US disclosed
US-8309754-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-11-13 US disclosed
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
EP-1948713-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM Bezwada Biomedical LLC (US) 2008-07-30 EP disclosed
WO-2007047244-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 TSHR 3176/4885TACR1 475/4885ACACB 4483/4885
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 TSHR 3176/4885TACR1 475/4885ACACB 4483/4885
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 TSHR 3176/4885TACR1 475/4885ACACB 4483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.