SCHEMBL313634

SCHEMBL313634

COC(=O)COC(=O)C(Cc1ccc(O)cc1)NC(C)=O

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 3/20 0.51
NPSR1 Q6W5P4 2/20 0.49
KMT2A Q03164 1/20 0.49
LNPEP Q9UIQ6 3/20 0.48
TSHR P16473 1/20 0.48
MDM4 O15151 1/20 0.48
MDM2 Q00987 1/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
GRIA1 P42261 1/20 0.46
NLRP3 Q96P20 1/20 0.45
ERAP2 Q6P179 2/20 0.43
ERAP1 Q9NZ08 1/20 0.43
ALDH1A1 P00352 1/20 0.43
FOLH1 Q04609 1/20 0.43
KDR P35968 1/20 0.42
MIF P14174 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3050135 0.87 NPSR1 (0.61) TACR1NPSR1KMT2ALNPEPTSHR
SCHEMBL2522737 0.87 NPSR1 (0.61) TACR1NPSR1KMT2ALNPEPTSHR
SCHEMBL315117 0.87 NPSR1 (0.61) TACR1NPSR1KMT2ALNPEPTSHR
SCHEMBL313085 0.86 ITGB3 (0.50) TACR1KMT2AALDH1A1
SCHEMBL314059 0.86 MDM4 (0.52) NPSR1KMT2ALNPEPTSHRMDM4
SCHEMBL313677 0.84 ITGB3 (0.48) TACR1KMT2AALDH1A1
Acetyl Tyrosine Ethyl Ester SCHEMBL468858 0.84 TACR1 (0.58) TACR1NPSR1KMT2ALNPEPTSHR
Acetyl Tyrosine Ethyl Ester SCHEMBL14370511 0.84 TACR1 (0.58) TACR1NPSR1KMT2ALNPEPTSHR
Acetyl Tyrosine Ethyl Ester SCHEMBL468756 0.84 TACR1 (0.58) TACR1NPSR1KMT2ALNPEPTSHR
SCHEMBL313678 0.83 TSHR (0.44) TACR1KMT2ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
EP-1948713-B1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2013-12-04 EP disclosed
US-20130317118-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-11-28 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-01-31 US disclosed
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-01-31 US disclosed
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
EP-1948713-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM Bezwada Biomedical LLC (US) 2008-07-30 EP disclosed
WO-2007047244-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-04-26 WO disclosed
WO-2007047244-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 TACR1 475/4885NPSR1 306/4885KMT2A 3572/4885
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 TACR1 475/4885NPSR1 306/4885KMT2A 3572/4885
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 TACR1 475/4885NPSR1 306/4885KMT2A 3572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.