Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.59 |
| ▸ | HNF4A | P41235 | 2/20 | 0.59 |
| ▸ | DHFR | P00374 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.53 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.53 |
| ▸ | ACLY | P53396 | 7/20 | 0.51 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | RXRB | P28702 | 2/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582859 | 1.00 | ACMSD (0.59) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| SCHEMBL940864 | 0.92 | RXRB (0.54) | ACMSDHNF4ADHFRMCL1ACLY | |
| SCHEMBL31000476 | 0.92 | RXRB (0.54) | ACMSDHNF4ADHFRMCL1ACLY | |
| SCHEMBL27702500 | 0.91 | RXRA (0.49) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| SCHEMBL28566197 | 0.88 | KIF11 (0.50) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| SCHEMBL30131558 | 0.88 | IKBKB (0.56) | ACMSDHNF4ADHFRMCL1ACLY | |
| SCHEMBL27633639 | 0.87 | ACMSD (0.58) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| SCHEMBL272323 | 0.86 | RXRA (0.55) | ACLYRXRARXRB | |
| SCHEMBL8920290 | 0.85 | RXRA (0.50) | ACMSDHNF4ADHFRMCL1RXRA | |
| SCHEMBL2794241 | 0.85 | MCL1 (0.60) | ACMSDHNF4AMCL1DCLRE1BACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144520-B | Enhanced nucleic acid polymerization by aromatic compounds | 豪夫迈·罗氏有限公司 | 2024-12-13 | — | — | CN | claimed |