Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | RXRB | P28702 | 3/20 | 0.50 |
| ▸ | RXRG | P48443 | 2/20 | 0.50 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 2/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924033 | 0.94 | RXRA (0.50) | RXRARXRBRXRGASPHCES2 | |
| SCHEMBL31000476 | 0.92 | RXRB (0.54) | RXRARXRBRXRGASPHCES2 | |
| SCHEMBL940864 | 0.92 | RXRB (0.54) | RXRARXRBRXRGASPHCES2 | |
| SCHEMBL27633639 | 0.87 | ACMSD (0.58) | RXRARXRBRXRGFABP4KIF11 | |
| SCHEMBL3582859 | 0.85 | ACMSD (0.59) | RXRARXRBRXRGFABP4HNF4A | |
| SCHEMBL31369064 | 0.85 | ACMSD (0.59) | RXRARXRBRXRGFABP4HNF4A | |
| SCHEMBL272323 | 0.80 | RXRA (0.55) | RXRARXRBCES2KDM4EKMT2A | |
| SCHEMBL3036944 | 0.80 | ASPH (0.59) | RXRARXRBASPHCES2KDM4E | |
| SCHEMBL8923156 | 0.79 | RXRB (0.49) | RXRARXRBRXRGKDM4EGFER | |
| SCHEMBL2794241 | 0.78 | MCL1 (0.60) | RXRARXRBRXRGKDM4EGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0708149-A1 | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-24 | — | — | EP | disclosed |