SCHEMBL404718

SCHEMBL404718

CCCCCCOc1c(CC)cccc1-c1nc(-c2ccccc2OC)nc(-c2cccc(CC)c2OCCCCCC)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.41
ADORA3 P0DMS8 2/20 0.41
ADORA1 P30542 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
ALOX15 P16050 2/20 0.41
TSHR P16473 2/20 0.41
CYP2C19 P33261 2/20 0.41
HSD17B10 Q99714 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
SCN8A Q9UQD0 1/20 0.40
ALOX5 P09917 1/20 0.40
PTGS2 P35354 1/20 0.40
PAX8 Q06710 1/20 0.40
TLR8 Q9NR97 1/20 0.40
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
HPGD P15428 2/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2709504 0.94 CYP1A2 (0.41) PPARAADORA3ADORA1CYP1A2CYP3A4
SCHEMBL16650037 0.86 ELANE (0.45) ADORA3ADORA1CYP3A4HSD17B10ALOX5
SCHEMBL627672 0.83 CYP1A2 (0.39) ADORA3ADORA1CYP1A2CYP3A4CYP2D6
SCHEMBL3137392 0.81 ELANE (0.43) ADORA3ADORA1CYP1A2CYP3A4CYP2D6
SCHEMBL17294439 0.81 THRA (0.35) PPARATLR8MCHR1
SCHEMBL1697181 0.78 LMNA (0.37) TSHRSMN1; SMN2LMNAMAPT
Guaiacol SCHEMBL3959515 0.76 ALOX5 (0.49) PPARACYP1A2CYP3A4CYP2D6TSHR
SCHEMBL697379 0.75 PDE5A (0.39) CYP3A4TLR8LMNAMAPTPDE5A
SCHEMBL3434962 0.74 ELANE (0.33) PPARASMN1; SMN2TLR8LMNAMAPT
SCHEMBL15162949 0.74 ELANE (0.38) PPARAHSD17B10ALOX5PTGS2TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024106520-A1 NON-STICKY STABLE COMPOSITION WITH TEXTURE TRANSFORMATION PROPERTY L'OREAL (FR) 2024-05-23 WO claimed
EP-3393437-B1 PHOTOPROTECTIVE COMPOSITION BASED ON A CARBOXYLIC ACID ESTER; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR OREAL (FR) 2023-06-07 EP claimed
US-10918583-B2 Cosmetic or dermatological composition comprising a merocyanine, an organic UVB-screening agent and an additional organic UVA-screening agent L'OREAL (FR) 2021-02-16 US claimed
EP-3193816-B1 COMPOSITION BASED ON MULTILAYER SPHERICAL COMPOSITE PARTICLES AND ON A UV-SCREENING AGENT OREAL (FR) 2020-05-13 EP claimed
US-20190336421-A1 COMPOSITION COMPRISING RESORCINOL OR DERIVATIVE THEREOF L'OREAL (FR) 2019-11-07 US claimed
EP-2775994-B1 COMPOSITION WITH A CONTINUOUS OIL PHASE CONTAINING AT LEAST ONE LIPOPHILIC ORGANIC UV-SCREENING AGENT AND HYDROPHOBIC SILICA AEROGEL PARTICLES OREAL (FR) 2019-10-16 EP claimed
EP-3016631-B1 COSMETIC COMPOSITION OREAL (FR) 2019-10-02 EP claimed
US-10272021-B2 Composition based on multilayer spherical composite particles and on a UV-screening agent L'OREAL (FR) 2019-04-30 US claimed
US-20180369094-A1 PHOTOPROTECTIVE COMPOSITION BASED ON A CARBOXYLIC ACID ESTER; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR L'OREAL (FR) 2018-12-27 US claimed
EP-1649901-B1 Light screening composition comprising a dibenzoylmethane derivative, a lipophilic amide and a compound capable of accepting energy from the excited triplet state of dibenzoylmethane; process for photostabilsation OREAL (FR) 2018-11-28 EP claimed
WO-2013084184-A2 PHOTOPROTECTIVE AND SELF-TANNING COSMETIC EMULSIONS L'OREAL (FR) 2013-06-13 WO claimed
WO-2013068237-A1 COMPOSITION WITH A CONTINUOUS OIL PHASE CONTAINING AT LEAST ONE LIPOPHILIC ORGANIC UV-SCREENING AGENT AND HYDROPHOBIC SILICA AEROGEL PARTICLES L'OREAL (FR) 2013-05-16 WO claimed
US-20130058990-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT L'OREAL (FR) 2013-03-07 US claimed
EP-2547313-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT L'Oréal (FR) 2013-01-23 EP claimed
WO-2012168102-A2 ANHYDROUS ANTISUN CREAM COMPRISING A NON-EMULSIFYING ELASTOMERIC ORGANOPOLYSILOXANE, A MATTING AGENT AND A NON-SILICONE ORGANIC OIL THICKENER L'OREAL (FR) 2012-12-13 WO claimed
EP-2174644-B1 Cosmetic composition comprising a dibenzoylmethane derivative and a dithiolane; Photostabilization of a dibenzoylmethane derivative OREAL (FR) 2012-11-14 EP claimed
WO-2011113718-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT L'OREAL (FR) 2011-09-22 WO claimed
US-20100172944-A1 COMBINATION OF MONOSACCHARIDES WITH SUNSCREENS AND USE THEREOF L'OREAL (FR) 2010-07-08 US claimed
US-20100086502-A1 Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor L'OREAL (FR) 2010-04-08 US claimed
US-20090285868-A1 Photostable cosmetic compositions comprising dibenzoylmethane/pyrrolidinone compounds L'OREAL (FR) 2009-11-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190336421-A1 COMPOSITION COMPRISING RESORCINOL OR DERIVATIVE THEREOF NQO1, LRAT, RBP4 PPARA 179/4885ADORA3 1640/4885ADORA1 1231/4885
US-20100086502-A1 Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor NOTUM, DDT, FDFT1 PPARA 1224/4885ADORA3 4556/4885ADORA1 3417/4885
US-20090285868-A1 Photostable cosmetic compositions comprising dibenzoylmethane/pyrrolidinone compounds NOTUM, CYP51A1, DHPS PPARA 42/4885ADORA3 4006/4885ADORA1 2369/4885
US-10272021-B2 Composition based on multilayer spherical composite particles and on a UV-screening agent CUTA, RAD52, PSMC3 PPARA 3380/4885ADORA3 2042/4885ADORA1 1698/4885
US-20130058990-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT CRYZ, MSH6, TYR PPARA 1457/4885ADORA3 2384/4885ADORA1 1377/4885
US-10918583-B2 Cosmetic or dermatological composition comprising a merocyanine, an organic UVB-screening agent and an additional organic UVA-screening agent KRT18, CRYZ, CUTA PPARA 1005/4885ADORA3 2137/4885ADORA1 1893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.