SCHEMBL1722952

SCHEMBL1722952

CCCCC(OC)(C(=O)c1ccccc1)C(=O)c1ccccc1.CCCCCCOc1c(-c2ncnc(-c3ccccc3OC)n2)ccc(CC)c1CC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.35
CNR2 P34972 3/20 0.35
CNR1 P21554 2/20 0.35
PPARA Q07869 1/20 0.34
PTPN11 Q06124 3/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
NR1I2 O75469 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADRA2A P08913 1/20 0.33
OPRK1 P41145 1/20 0.33
HTR2B P41595 1/20 0.33
SLC6A3 Q01959 1/20 0.33
KMT2A Q03164 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
PDE4B Q07343 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL627672 0.87 CYP1A2 (0.39) CNR2CNR1LMNAMEN1CYP3A4
SCHEMBL3046346 0.80 PAX8 (0.39) PAX8CNR2CNR1PPARALMNA
SCHEMBL3137392 0.78 ELANE (0.43) PAX8CNR2CNR1LMNAMAPT
SCHEMBL2709504 0.77 CYP1A2 (0.41) PAX8PPARAMAPTCYP3A4PDE4B
SCHEMBL15796889 0.75 PTPN11 (0.33) CNR2CNR1PTPN11
SCHEMBL3151383 0.74 PDE5A (0.34) CNR2MEN1KMT2APDE4BELANE
SCHEMBL16650037 0.72 ELANE (0.45) PAX8CNR2CNR1LMNAMAPT
SCHEMBL32681987 0.72 PTPN11 (0.45) PPARAPTPN11LMNAMAPTMEN1
SCHEMBL404718 0.72 PPARA (0.41) PAX8PPARALMNAMAPTCYP3A4
SCHEMBL6399457 0.72 SOAT1 (0.37) PTPN11MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2344112-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2011-07-20 EP claimed
US-20100129303-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2010-05-27 US claimed
WO-2010043588-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2010-04-22 WO claimed
EP-3471694-A1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS Johnson & Johnson Consumer Inc. (US) 2019-04-24 EP disclosed
WO-2017218390-A1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS JOHNSON & JOHNSON CONSUMER INC. (US) 2017-12-21 WO disclosed
EP-2344112-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2011-07-20 EP disclosed
US-20100129303-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2010-05-27 US disclosed
WO-2010043588-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2010-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100129303-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER MITF, TYR, MSH6 PAX8 2881/4885CNR2 3554/4885CNR1 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.