SCHEMBL2709504

SCHEMBL2709504

CCCCCCOc1c(CC)cccc1-c1ncnc(-c2ccccc2OC)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
CYP2C19 P33261 1/20 0.41
PPARA Q07869 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
PAX8 Q06710 1/20 0.38
SCN8A Q9UQD0 1/20 0.38
ALOX5 P09917 1/20 0.38
PTGS2 P35354 1/20 0.38
TLR8 Q9NR97 1/20 0.38
HPGD P15428 2/20 0.37
ADORA3 P0DMS8 1/20 0.37
ADORA1 P30542 1/20 0.37
PDE5A O76074 1/20 0.37
PDE4A P27815 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL404718 0.94 PPARA (0.41) CYP1A2CYP3A4CYP2D6HSD17B10ALOX15
SCHEMBL627672 0.89 CYP1A2 (0.39) CYP1A2CYP3A4CYP2D6HSD17B10ALOX15
SCHEMBL17294439 0.87 THRA (0.35) PPARATLR8
SCHEMBL3137392 0.87 ELANE (0.43) CYP1A2CYP3A4CYP2D6HSD17B10ALOX15
SCHEMBL16650037 0.81 ELANE (0.45) CYP3A4HSD17B10ALDH1A1PAX8ALOX5
SCHEMBL1697181 0.80 LMNA (0.37) TSHRSMN1; SMN2MAPT
SCHEMBL1722952 0.77 PAX8 (0.35) CYP3A4PPARAPAX8ADORA3ADORA1
SCHEMBL3434962 0.76 ELANE (0.33) PPARASMN1; SMN2TLR8MAPT
SCHEMBL30497724 0.74 CYP1A2 (0.57) CYP1A2CYP2C19TLR8PDE5APDE4A
SCHEMBL3134741 0.74 SGMS2 (0.34) CYP3A4ALOX5PDE5APDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3148507-A1 COSMETIC COMPOSITIONS WITH ENHANCED COLOR RETENTION FOR IMPROVED SKIN APPEARANCE Edgewell Personal Care Brands, LLC (US) 2017-04-05 EP claimed
WO-2015184071-A1 COSMETIC COMPOSITIONS WITH ENHANCED COLOR RETENTION FOR IMPROVED SKIN APPEARANCE EVEREADY BATTERY COMPANY, INC (US) 2015-12-03 WO claimed
WO-2021102113-A1 SUNSCREEN COMPOSITIONS WITH MULTIPLE PHOTOPROTECTING UV FILTERS COTY INC. (US) 2021-05-27 WO disclosed
EP-3151923-A1 CLEAR COMPOSITIONS AND METHODS FOR THE DELIVERY OF ACTIVE INGREDIENTS FOR SKIN CARE Arbonne International LLC (US) 2017-04-12 EP disclosed
EP-3148507-A1 COSMETIC COMPOSITIONS WITH ENHANCED COLOR RETENTION FOR IMPROVED SKIN APPEARANCE Edgewell Personal Care Brands, LLC (US) 2017-04-05 EP disclosed
WO-2015187921-A1 CLEAR COMPOSITIONS AND METHODS FOR THE DELIVERY OF ACTIVE INGREDIENTS FOR SKIN CARE ARBONNE INTERNATIONAL, LLC (US) 2015-12-10 WO disclosed
WO-2015184071-A1 COSMETIC COMPOSITIONS WITH ENHANCED COLOR RETENTION FOR IMPROVED SKIN APPEARANCE EVEREADY BATTERY COMPANY, INC (US) 2015-12-03 WO disclosed
EP-2701670-A1 CLEAR WET SPRAYS AND GELS Isp Investments Inc. (US) 2014-03-05 EP disclosed
WO-2012149355-A1 CLEAR WET SPRAYS AND GELS ISP INVESTMENTS INC. (US) 2012-11-01 WO disclosed
EP-2445480-A2 EXTRACT OF WHOLE SEEDS OF MORINGA SP, AND USE THEREOF IN COSMETIC AND/OR DERMATOLOGICAL COMPOSITIONS Pierre Fabre Dermo-Cosmétique (FR) 2012-05-02 EP disclosed
WO-2010149895-A2 EXTRACT OF WHOLE SEEDS OF MORINGA SP., AND USE THEREOF IN COSMETIC AND/OR DERMATOLOGICAL COMPOSITIONS PIERRE FABRE DERMO-COSMETIQUE (FR) 2010-12-29 WO disclosed