Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1813640 | 0.84 | NR1H2 (0.43) | NR3C1POLBSMN1; SMN2RORCALDH1A1 | |
| SCHEMBL13885185 | 0.79 | POLB (0.45) | NR3C1POLBHSD11B1SMN1; SMN2HDAC6 | |
| SCHEMBL3252349 | 0.78 | NR3C1 (0.43) | NR3C1HSD11B1HDAC6RORCUSP2 | |
| SCHEMBL28024715 | 0.74 | POLB (0.48) | POLBHSD11B1SMN1; SMN2GRM5KCNN4 | |
| SCHEMBL13736869 | 0.74 | RORC (0.55) | NR3C1POLBHSD11B1SMN1; SMN2HDAC6 | |
| SCHEMBL699259 | 0.71 | SMN1; SMN2 (0.50) | POLBSMN1; SMN2ALDH1A1TP53CYP3A4 | |
| SCHEMBL5149151 | 0.71 | ESR1 (0.45) | NR3C1HSD11B1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL2317622 | 0.70 | TSHR (0.44) | NR3C1POLBHSD11B1ALDH1A1CYP3A4 | |
| SCHEMBL1816541 | 0.70 | POLB (0.52) | POLBHSD11B1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11598682 | 0.70 | RAB9A (0.52) | NR3C1HSD11B1SMN1; SMN2KCNN4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618173-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2013-12-31 | — | — | US | disclosed |
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| CN-101827521-A | Bisamide derivatives and as the purposes of insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2010-09-08 | — | — | CN | disclosed |
| EP-2203052-A2 | BISAMIDE DERIVATIVES AND THEIR USE AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009049845-A2 | BISAMIDE DERIVATIVES AND THEIR USE AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049845-A2 | BISAMIDE DERIVATIVES AND THEIR USE AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, ACHE | NR3C1 4171/4885POLB 4760/4885HSD11B1 3941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.