Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.42 |
| ▸ | PGR | P06401 | 4/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11414795 | 0.83 | PGR (0.44) | SMN1; SMN2POLBNR1H2NR1H3PGR | |
| SCHEMBL1819523 | 0.83 | PGR (0.45) | SMN1; SMN2ALDH1A1NR1H2NR1H3PGR | |
| SCHEMBL11275397 | 0.83 | POLB (0.45) | SMN1; SMN2POLBTSHRALDH1A1TP53 | |
| SCHEMBL1816541 | 0.80 | POLB (0.52) | SMN1; SMN2POLBTSHRALDH1A1TP53 | |
| SCHEMBL7104195 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRNR1H2NR1H3PGR | |
| SCHEMBL11126670 | 0.79 | ESR1 (0.46) | SMN1; SMN2TSHRNR1H2NR1H3PGR | |
| SCHEMBL11306411 | 0.78 | POLB (0.45) | SMN1; SMN2POLBTSHRALDH1A1TP53 | |
| SCHEMBL11321037 | 0.77 | NR1H2 (0.44) | SMN1; SMN2TSHRNR1H2NR1H3PGR | |
| SCHEMBL8586265 | 0.77 | NR1H2 (0.48) | SMN1; SMN2TSHRNR1H2NR1H3PGR | |
| SCHEMBL7101194 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373947-A1 | AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE | MITSUI CHEMICALS, INC. (JP) | 2023-11-23 | — | — | US | disclosed |
| US-11760742-B2 | Amide derivatives, process for preparation thereof and use thereof as insecticide | MITSUI CHEMICALS, INC. (JP) | 2023-09-19 | — | — | US | disclosed |
| EP-2423188-B1 | Intermediates in the preparation of agricultural/horticultural insecticides and method for using the same | MITSUI CHEMICALS AGRO INC (JP) | 2021-03-10 | — | — | EP | disclosed |
| US-10435385-B2 | Amide derivatives, process for preparation thereof and use thereof as insecticide | MITSUI CHEMICALS, INC. (JP) | 2019-10-08 | — | — | US | disclosed |
| CN-105980353-B | ROR gamma modulators | 领先制药控股公司 | 2019-06-14 | — | — | CN | disclosed |
| EP-3077372-B1 | ROR GAMMA (RORY) MODULATORS | LEAD PHARMA HOLDING BV (NL) | 2019-02-06 | — | — | EP | disclosed |
| US-20180134681-A1 | AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE | MITSUI CHEMICALS, INC. (JP) | 2018-05-17 | — | — | US | disclosed |
| US-9920026-B2 | Amide derivatives, process for preparation thereof and use thereof as insecticide | MITSUI CHEMICALS, INC. (JP) | 2018-03-20 | — | — | US | disclosed |
| US-9738600-B2 | ROR gamma (RORγ) modulators | LEAD PHARMA CEL MODELS IP B.V. (NL) | 2017-08-22 | — | — | US | disclosed |
| US-9738600-B2 | ROR gamma (RORγ) modulators | LEAD PHARMA CEL MODELS IP B.V. (NL) | 2017-08-22 | — | — | US | disclosed |
| US-20090192167-A1 | Insecticidal and fungicidal composition | MITSUI CHEMICALS, INC. (JP) | 2009-07-30 | — | — | US | disclosed |
| US-20090162453-A1 | COMPOSITION FOR PREVENTING HARMFUL ORGANISMS | MITSUI CHEMICALS, INC (JP) | 2009-06-25 | — | — | US | disclosed |
| US-20070027154-A1 | Insecticide for agricultural or horticultural use and method of use thereof | MITSUI CHEMICALS., INC. (JP) | 2007-02-01 | — | — | US | disclosed |
| EP-1661886-A1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |
| EP-1161233-A2 | LXR MODULATORS | Tularik Inc. (US) | 2001-12-12 | — | — | EP | disclosed |
| US-6316503-B1 | LXR modulators | TULARIK INC. | 2001-11-13 | — | — | US | disclosed |
| WO-2000054759-A2 | LXR MODULATORS | TULARIK INC. (US) | 2000-09-21 | — | — | WO | disclosed |
| US-4272550-A | Omega-[4-(polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio]alkanoic acids and compounds related thereto | SCHERING CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |
| US-4199597-A | Omega-(4-polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio)alkanoic acids and compounds related thereto | SCHERING CORPORATION (US) | 1980-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134681-A1 | AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE | CYP1A1, CYP4B1, CYP2E1 | SMN1; SMN2 2650/4885POLB 2928/4885TSHR 519/4885 |
| US-20090192167-A1 | Insecticidal and fungicidal composition | NOX3, PRDX1, CYP4X1 | SMN1; SMN2 720/4885POLB 4499/4885TSHR 2076/4885 |
| US-20070027154-A1 | Insecticide for agricultural or horticultural use and method of use thereof | CBR3, ATL3, CNPY2 | SMN1; SMN2 2549/4885POLB 4471/4885TSHR 1222/4885 |
| US-20230373947-A1 | AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE | DDT, CYP4B1, CYP2E1 | SMN1; SMN2 3108/4885POLB 4176/4885TSHR 2017/4885 |
| US-10435385-B2 | Amide derivatives, process for preparation thereof and use thereof as insecticide | DDT, CYP4B1, CYP2E1 | SMN1; SMN2 3108/4885POLB 4176/4885TSHR 2017/4885 |
| US-20090162453-A1 | COMPOSITION FOR PREVENTING HARMFUL ORGANISMS | PRDX3, CYP1A1, GSTA1 | SMN1; SMN2 1073/4885POLB 2739/4885TSHR 2265/4885 |
| US-11760742-B2 | Amide derivatives, process for preparation thereof and use thereof as insecticide | DDT, CYP4B1, CYP2E1 | SMN1; SMN2 3108/4885POLB 4176/4885TSHR 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.