Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27739880 | 0.74 | LMNA (0.39) | PAX8ALDH1A1HPGDEGFRMTNR1A | |
| SCHEMBL27837408 | 0.74 | CHRNB4 (0.35) | PAX8CCKBRMAPTKCNH2GAA | |
| SCHEMBL19158834 | 0.72 | POLB (0.47) | PAX8ALDH1A1SMN1; SMN2HPGDEGFR | |
| SCHEMBL3042387 | 0.72 | MTNR1A (0.40) | PAX8ALDH1A1HPGDEGFRMTNR1A | |
| SCHEMBL3004854 | 0.72 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDMTNR1AMTNR1B | |
| SCHEMBL9038555 | 0.72 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDMTNR1AMTNR1B | |
| SCHEMBL31378005 | 0.70 | PAX8 (0.33) | PAX8KCNH2 | |
| SCHEMBL11049443 | 0.70 | KCNH2 (0.33) | PAX8CCKBRKCNH2 | |
| SCHEMBL13315859 | 0.68 | HTR2C (0.39) | ALDH1A1HPGDMAPTGAA | |
| SCHEMBL22864722 | 0.68 | HPGD (0.33) | PAX8ALDH1A1HPGDCCKBRMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101304989-A | Carbocyclic fused cyclic amines as inhibitors of the coagulation factor XA | HOFFMANN LA ROCHE (CH) | 2008-11-12 | — | — | CN | disclosed |