Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31380355 | 0.76 | HDAC1 (0.40) | DRD1CYP4F2CYP4A11 | |
| SCHEMBL31380397 | 0.72 | CYP11B2 (0.36) | IRAK4 | |
| SCHEMBL31380346 | 0.72 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL31380372 | 0.69 | IRAK4 (0.33) | IRAK4 | |
| SCHEMBL31380312 | 0.68 | MBOAT4 (0.33) | IRAK4 | |
| SCHEMBL31380405 | 0.66 | IRAK4 (0.36) | IRAK4 | |
| SCHEMBL31380354 | 0.66 | CYP11B1 (0.38) | IRAK4 | |
| SCHEMBL31380381 | 0.65 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL4073537 | 0.65 | ACHE (0.35) | IRAK4 | |
| SCHEMBL31380323 | 0.64 | LTA4H (0.37) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707931-A | Intermediate and synthesis method of 1- (1-oxo-1, 2-dihydro-phthalazin-6-yl) cycloalkyl-1-carboxamide derivatives as MTA synergistic inhibitors of PRMT5 | 百济神州(北京)生物科技有限公司 | 2025-03-28 | — | — | CN | disclosed |