SCHEMBL3138864

SCHEMBL3138864

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nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGAM O43451 3/20 0.38
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
PDE4A P27815 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14377638 0.83 MGAM (0.42) MGAMLMNAL3MBTL1TDP1PDE4A
SCHEMBL14413769 0.83 MGAM (0.42) MGAMLMNAL3MBTL1TDP1PDE4A
SCHEMBL7590412 0.77 LMNA (0.46) MGAMLMNAL3MBTL1TDP1PDE4A
SCHEMBL8486 0.76 LMNA (0.39) LMNAL3MBTL1TDP1PDE4A
SCHEMBL599665 0.76 LMNA (0.39) LMNAL3MBTL1TDP1PDE4A
SCHEMBL3851271 0.76 LMNA (0.39) LMNAL3MBTL1TDP1PDE4A
SCHEMBL2848010 0.76 LMNA (0.39) LMNAL3MBTL1TDP1PDE4A
SCHEMBL8718435 0.76 LMNA (0.39) LMNAL3MBTL1TDP1PDE4A
SCHEMBL15754346 0.76 LMNA (0.39) LMNAL3MBTL1TDP1PDE4A
SCHEMBL2316300 0.76 LMNA (0.39) MGAMLMNAL3MBTL1TDP1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1175907-A1 REMEDIES Takara Shuzo Co, Ltd. (JP) 2002-01-30 EP claimed
US-7816134-B2 Method of extensive culture of antigen-specific cytotoxic T cells TAKARA BIO INC. (JP) 2010-10-19 US disclosed
US-7678368-B2 Fucoidan-containing cosmetics TAKARA BIO INC. (JP) 2010-03-16 US disclosed
EP-1234568-B1 Use of fucoidan as effective hair restoring ingredient TAKARA BIO INC (JP) 2008-07-23 EP disclosed
US-20080166325-A1 Method of extensive culture of antigen-specific cytotoxic T cells SAGAWA HIROAKI 2008-07-10 US disclosed
US-20060093566-A1 Fucoidan-containing cosmetics MIZUTANI SHIGETOSHI 2006-05-04 US disclosed
US-20060051316-A1 Remedy TAKARA BIO INC. (JP) 2006-03-09 US disclosed
EP-1570845-A1 REMEDY TAKARA BIO INC. (JP) 2005-09-07 EP disclosed
US-20040115809-A1 Method of extensive culture of antigen-specific cytotoxic t cells TAKARA BIO INC. (JP) 2004-06-17 US disclosed
EP-1312670-A1 METHOD OF EXTENSIVE CULTURE OF ANTIGEN-SPECIFIC CYTOTOXIC T CELLS TAKARA BIO INC. (JP) 2003-05-21 EP disclosed
US-20030039670-A1 Cosmetics TAKARA BIO INC. (JP) 2003-02-27 US disclosed
EP-1234568-A1 COSMETICS Takara Shuzo Co, Ltd. (JP) 2002-08-28 EP disclosed
EP-1175907-A1 REMEDIES Takara Shuzo Co, Ltd. (JP) 2002-01-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030039670-A1 Cosmetics FUCA1, GLA, TYR MGAM 679/4885LMNA 2088/4885L3MBTL1 3677/4885
US-20060051316-A1 Remedy BMP2, BMP4, BMP1 MGAM 41/4885LMNA 3595/4885L3MBTL1 3127/4885
US-20060093566-A1 Fucoidan-containing cosmetics FUCA1, FUCA2, FUT5 MGAM 756/4885LMNA 1966/4885L3MBTL1 3865/4885
US-20080166325-A1 Method of extensive culture of antigen-specific cytotoxic T cells CD44, ALG1, CD47 MGAM 182/4885LMNA 3986/4885L3MBTL1 1944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.